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    Glossary Wnt antagonist

    substance that blocks Wnt signaling, affecting cell growth

    A Wnt antagonist is a substance that inhibits the Wnt signaling pathway, which is crucial for various biological processes including cell growth, development, and hair follicle formation. By blocking this pathway, Wnt antagonists can affect hair growth and are being studied for their potential in treating conditions like alopecia.

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    Research 30 of 1000+

    1. Androgens modify Wnt agonists/antagonists expression balance in dermal papilla cells preventing hair follicle stem cell differentiation in androgenetic alopecia Molecular and Cellular Endocrinology · 2016 · 47 citations
    2. The role of dexamethasone in mediating the contradictory effects of Wnt antagonists SFRP2 and SFRP3 on human hair follicle growth Scientific reports · 2023
    3. 195 Androgen action and 3D culture conditions influence dermal papilla cells inductive properties: the role of Wnt agonists/antagonists balance Journal of Investigative Dermatology · 2016
    4. THE ROLE OF AGONISTS AND ANTAGONISTS OF THE WNT SIGNALING PATHWAY IN PATIENTS WITH ANDROGENIC ALOPECIA AND ALOPECIA AREATA Медико-фармацевтический журнал "Пульс" · 2021
    5. Bone Morphogenetic Protein Antagonist Noggin Promotes Skin Tumorigenesis via Stimulation of the Wnt and Shh Signaling Pathways American Journal Of Pathology · 2009 · 45 citations
    6. The Androgen Receptor Antagonizes Wnt/β-Catenin Signaling in Epidermal Stem Cells Journal of Investigative Dermatology · 2015 · 46 citations
    7. Faculty Opinions recommendation of Bone morphogenetic protein antagonist noggin promotes skin tumorigenesis via stimulation of the Wnt and Shh signaling pathways. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · 2009
    8. Targeting Endogenous Wnt Antagonists for Therapy Development in AGA: a Focus on DKKs and sFRPs Stem Cell Reviews and Reports · 2026
    9. Human CD133 <sup>+</sup> Progenitor Cells Promote the Healing of Diabetic Ischemic Ulcers by Paracrine Stimulation of Angiogenesis and Activation of Wnt Signaling Circulation Research · 2009 · 245 citations
    10. Liposomal Packaging Generates Wnt Protein with In Vivo Biological Activity PLOS ONE · 2008 · 75 citations
    11. Wnt signaling: the good and the bad Acta Biochimica et Biophysica Sinica · 2008 · 48 citations
    12. 447 Skin-Associated Cartilage Consists of Lipid-Filled Cells That Modify Hair Growth via BMP and WNT Signaling Journal of Investigative Dermatology · 2025
    13. Involvement of Wnt, Eda and Shh at defined stages of sweat gland development Development · 2014 · 55 citations
    14. Suppression of Wnt/β-catenin signaling by EGF receptor is required for hair follicle development Molecular Biology of the Cell · 2018 · 25 citations
    15. Mycophenolate Antagonizes IFN-γ-Induced Catagen-Like Changes via β-Catenin Activation in Human Dermal Papilla Cells and Hair Follicles International Journal of Molecular Sciences · 2014 · 11 citations
    16. Androgenetic alopecia: combing the hair follicle signaling pathways for new therapeutic targets and more effective treatment options Expert Opinion on Therapeutic Targets · 2019 · 19 citations
    17. Decision letter: A multi-scale model for hair follicles reveals heterogeneous domains driving rapid spatiotemporal hair growth patterning 2017
    18. New investigational drugs for androgenetic alopecia Expert Opinion on Investigational Drugs · 2013 · 48 citations
    19. A bald statement - Current approaches to manipulate miniaturisation focus only on promoting hair growth Experimental Dermatology · 2018 · 30 citations
    20. CCN2 modulates hair follicle cycling in mice Molecular Biology of the Cell · 2013 · 21 citations
    21. Gene Expression Profiling of the Intact Dermal Sheath Cup of Human Hair Follicles Acta dermato-venereologica · 2018 · 11 citations
    22. New Treatments for Hair Loss Actas Dermo-Sifiliográficas · 2017 · 7 citations
    23. Pathogenic Mechanisms and Mechanism‐Directed Therapies for Androgenetic Alopecia: Current Understanding and Future Directions Dermatologic Therapy · 2025
    24. Тіе Modern treatment of androgenetic alopecia DOAJ (DOAJ: Directory of Open Access Journals) · 2017
    25. 700 Oncostatin M is upstream of JAK-STAT signaling during the murine hair cycle Journal of Investigative Dermatology · 2016
    26. Тіе Modern treatment of androgenetic alopecia Vestnik dermatologii i venerologii · 2017
    27. Serum Dicckopf-1 Level in Patients of Cicatricial and Non- Cicatricial Alopecia Benha Journal of Applied Sciences · 2022
    28. Bone Morphogenetic Protein Signaling Inhibits Hair Follicle Anagen Induction by Restricting Epithelial Stem/Progenitor Cell Activation and Expansion Stem Cells · 2006 · 176 citations
    29. Advances in hair growth Faculty reviews · 2022 · 1 citations
    30. 845 Dermal lymphatic vessels promote hair follicle growth via the BMP inhibitor Sostdc1 Journal of Investigative Dermatology · 2017