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    Signal Integrator Function of CXXC5 in Cancer

    January 2025 in “ Cell Communication and Signaling ”
    Zihao An, Jing Wang, Chang Li, Chao Tang
    Studysummary This study reviews the role of the zinc finger protein CXXC5 in cellular signaling and its implications for cancer, discussing how its dysregulation is linked to various physiological and pathological processes, as well as potential therapies targeting CXXC5.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 10

    1. Inhibiting the Cytosolic Function of CXXC5 Accelerates Diabetic Wound Healing by Enhancing Angiogenesis and Skin Repair Experimental & Molecular Medicine · 2023
    2. Pyruvate Kinase M2 Accelerates Cutaneous Wound Healing via Glycolysis and Wnt/β-Catenin Signaling Pharmaceutics · 2023
    3. KY19382 Accelerates Cutaneous Wound Healing Via Activation Of The Wnt/β-Catenin Signaling Pathway International Journal of Molecular Sciences · 2023
    4. Effect of DNA Aptamer Through Blocking of Negative Regulation of Wnt/Beta-Catenin Signaling in Human Hair Follicle Dermal Papilla Cells Skin research and technology · 2023
    5. CXXC5 Mediates DHT-Induced Androgenetic Alopecia via PGD2 Cells · 2023
    6. Wnt/β-Catenin Signaling: Function, Biological Mechanisms, and Therapeutic Opportunities Signal Transduction and Targeted Therapy · 2022
    7. KY19382, A Novel Activator of Wnt/β-Catenin Signalling, Promotes Hair Regrowth and Hair Follicle Neogenesis British Journal of Pharmacology · 2021
    8. CXXC5: A Novel Regulator and Coordinator of TGF-β, BMP, and Wnt Signaling Journal of Cellular and Molecular Medicine · 2018
    9. The Negative Regulator CXXC5: Making WNT Look a Little Less Disheveled Journal of Investigative Dermatology · 2017
    10. Targeting of CXXC5 by a Competing Peptide Stimulates Hair Regrowth and Wound-Induced Hair Neogenesis Journal of Investigative Dermatology · 2017