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This study found that baicalin delivery through polymeric nanocapsules significantly enhanced its anticancer activity in breast cancer cell lines MCF-7 and MDA-MB-231.

This article reviews current strategies and advancements in regenerating skin appendages and sensory nerves in tissue-engineered skin, highlighting the challenge of restoring skin sensations like pain, temperature, and touch to improve patients’ quality of life.

This study reports that a newly developed polyherbal phospholipid complex cream containing Citrus auranticum and Glycyrrhiza glabra extracts improved polyphenol retention in the skin, suggesting potential as an anti-aging cosmeceutical.

This study found that ethanol-containing formulations significantly increased minoxidil retention in the stratum corneum and appendages initially, while a propylene glycol-rich formulation enhanced deeper skin penetration over time.

This study found that Transcutol-containing vesicles improved the delivery of minoxidil to deeper skin layers in vitro but did not facilitate its permeation through the skin.

In this study, researchers isolated and identified diverse endophytes from plants in Asia, finding that these microorganisms have significant potential for producing useful metabolites, including enzymes and antibiotics.

Human enzymes can detoxify harmful substances but might also increase their cancer risk.

This study found that the contribution of the hair follicle pathway to skin permeation of chemicals can be predicted using lipophilicity, with hydrophilic chemicals showing greater permeation reduction from hair follicle plugging than lipophilic ones.

This study suggests that human keratin fiber matrix has a well-defined nano-scale grainy structure rather than being amorphous, with grain size influenced by chemical treatments, temperature, humidity, and follicle-level factors.

This study found that using drug microplates in transdermal finasteride films enhances aqueous solubility and skin permeation compared to films with pure finasteride.

This study found that solid lipid nanoparticles with minoxidil were as effective as commercial solutions for skin penetration and were non-corrosive, indicating potential for hair loss treatment.

In this study, Gaussian process regression models combined with Grey Wolf optimization were used to predict and optimize phenolic and flavonoid content extraction from Carthamus caeruleus L. rhizomes, showing high accuracy and helping improve understanding and extraction processes through a new interactive tool.

This study found that capped mesoporous silica nanoparticles conjugated with antibodies selectively released a dye when exposed to finasteride, with low detection limits and stable performance even after storage.

This study observed that higher childhood fluoride exposure was associated with delayed pubertal development in Mexican boys aged 10-17, with no significant effects found in girls.

Liposomes can make the antiandrogen RU 58841 more effective for skin application by reducing absorption, increasing skin retention, and targeting sebaceous structures.

This review discusses nanostructured lipid carriers and their potential applications in pharmaceuticals and food, offering no new clinical findings but highlighting recent advancements and patents.

This study discusses the potential of thermoresponsive nanogels for improving dermal delivery of therapeutics, highlighting their ability to enhance skin penetration and control drug release with minimal damage to the skin's natural barrier.

This study found that surface-modified liquid crystalline nanoparticles significantly enhanced skin permeation of finasteride and dutasteride compared to unmodified nanoparticles, suggesting potential for improved treatment efficacy in androgenetic alopecia.

This study found that a 2% polyherbal phyto-complex cream containing aqueous extracts of Trichosanthes cucumerina and Abrus precatorius effectively promoted hair growth in preclinical tests, comparable to minoxidil 2%.

This study found that the penetration enhancer SEPA™ significantly increased both the speed and amount of hair growth from minoxidil in balding stumptail macaques compared to Rogaine®.

This study reported that using 2D solid-state NMR techniques on extensively labeled mouse fur improves resolution in detecting chemical shifts and secondary structure features, potentially aiding the analysis of the effects of commercial or therapeutic treatments on specific amino acids.

Invasomes effectively deliver drugs through the skin and have potential for improved treatments.

This study found that short durations of heat and specific chemical penetration enhancers significantly improved the delivery of finasteride to human scalp skin and hair follicles.

In this study, the researchers reported that while both propylene glycol and sodium lauryl sulfate enhanced finasteride's skin deposition, ethanol was the only effective enhancer of finasteride's permeation through the skin.

This study found that platelet-rich plasma can transiently inhibit bacterial growth in vitro against multidrug-resistant strains from diabetic foot infections, although its efficacy diminished over time and did not affect biofilm formation.

This study found that an optimized microemulsion for minoxidil with high solubility, permeation flux, and skin deposition can be achieved with specific low and high levels of certain surfactants and co-solvents.

This study found that the ethanolic root extract of Onosma dichroantha exhibits antioxidant activity and significant antimicrobial effects against 11 bacterial species.

This case report study presents two instances of post-finasteride syndrome, highlighting the persistence of sexual adverse effects despite discontinuation of the drug, and underscores the need for increased awareness and understanding of this condition.

This study evaluated a new nanogel formulation containing Ciclopirox Olamine for treating cutaneous candidiasis, finding that the optimized version offered improved skin penetration, sustained drug release, and effective antifungal action against Candida albicans compared to conventional treatment.

This study formulated a nanogel with Bangkal bark extract that showed moderate antibacterial activity against Propionibacterium acnes, with the F3 formulation (8% extract) achieving the highest inhibition zone of 8 mm, suggesting potential as a natural acne treatment.