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This study found that GPC1 is a crucial regulator of angiogenesis in human dermal microvascular endothelial cells, indicating its potential as a target for treating alopecia.

This study found that VEGFR-2 activation may play a role in hair follicle differentiation, proliferation, and apoptosis by co-expressing with several key proteins in normal human scalp skin.

This study found that VEGF stimulates the proliferation of human hair follicle dermal papilla cells via the VEGFR-2/ERK pathway, without involving p38, JNK, or AKT signaling.

This study observed that VEGF165 increases proliferation and migration but alters adhesion properties of cultured human hair follicle cells, indicating a potential role for VEGF/VEGFR-2 in hair follicle regulation beyond angiogenesis.

This study found that phosphorylated VEGFR-2 is present in human scalp epidermal appendages and suggests it plays a role in their daily regulation.

This study found that a combination of vitamins in hair care products promoted hair shaft elongation in a mouse model by activating the PlGF/VEGFR-1 signaling pathway.

This study developed a dissolvable microneedle system delivering specific molecules to remodel lymphatic networks and normalize metabolic processes, which accelerated hair growth and activated hair follicle stem cells in a mouse model of androgenetic alopecia.

In this study, androgen was found to increase VEGF expression, but not VEGFR-2, in rat corpus cavernous, with DHT likely playing a key role.

In this Phase II study, BAY 43–9006, taken orally for renal cell carcinoma, stabilized disease in 30% of patients, with 40% responding positively, although the targets remain unclear.

This review examines the evolving understanding of lymphatic vessel development, emphasizing new cellular mechanisms and lineage diversity, while discussing experimental methods and identifying key knowledge gaps.

This study found that deoxyshikonin promoted wound healing in diabetic mice, suggesting it may contribute to wound repair in patients with diabetes.

This study found that human outer root sheath cells express VEGF receptor-2, and exogenous VEGF165 significantly stimulates their proliferation through activation of the ERK signaling pathway.

This study suggests that natural molecules like curcumin, EGCG, barringtozenol, and finasteride may be effective inhibitors for VEGFR, potentially offering a cancer chemoprevention alternative to pazopanib.

This study found that baicalin promotes human microvascular endothelial cell proliferation, while visnadin and minoxidil enhance tubulogenesis, with hesperidin uniquely increasing VEGFR-2 phosphorylation compared to other compounds tested.

This review discusses the adverse effects on hair associated with targeted cancer therapies and reports no new clinical results; it emphasizes the need for comprehensive documentation of these effects.

In this experimental study, the researchers observed that Platycladus orientalis leaf extract promoted hair growth by enhancing dermal papilla cell proliferation and increasing growth factor expression, particularly through ACK1 activation and modulation of Wnt/β-catenin signaling pathways in cultured human cells and a 12-week topical application.

This study found that GPC1 is a key regulator of angiogenesis in hair follicles and may be an interesting target for addressing alopecia in dermatology research.

This study found that GPC1 is a key regulator of angiogenesis in human dermal microvascular endothelial cells, influenced by factors secreted by keratinocytes, and may be a target for alopecia treatment research.

This study found that GPC1 plays a crucial role in regulating angiogenesis in human dermal microvascular endothelial cells, which may make it a potential target in alopecia treatment research.

This study found that GPC1 is a significant regulator of angiogenesis in human dermal microvascular endothelial cells, suggesting its potential as a target for alopecia research.

This research found that kaempferol, a flavonoid from hair growth-promoting plants, significantly enhanced human dermal papilla cell proliferation and inhibited specific signaling pathways, outperforming minoxidil, with topical application in mice promoting hair growth and thickness, indicating potential as a natural hair loss treatment.

This review details the skin and hematological toxicities of tyrosine kinase inhibitors like erlotinib, gefitinib, and imatinib, and highlights ongoing concerns about cardiac toxicity, reporting no new clinical findings.

This review discusses the skin side effects associated with targeted cancer therapies and reports no new clinical results; it emphasizes the need for empirical management based on expert opinion.

This study found that numerous genes involved in hair growth, including 73 co-up-regulated ones, were differentially expressed in goat hair follicles during the hair growth cycle.

This study demonstrates that LES-hair can detect differential protein expression in specific regions of plucked hair follicles, suggesting its potential for research and clinical applications like monitoring treatment effects in alopecia and cancer therapies.

This study found that micro needle roller therapy enhanced hair follicle development and increased growth factor expression in C57BL/6 mice, suggesting potential benefits for alopecia treatment.

This study reports that targeted anticancer therapies frequently cause skin-related side effects, which may impact patient adherence and quality of life, but these effects are positively correlated with treatment response.

This study found that specific genes related to vascular endothelial growth factors are critical for feather maturity in certain chicken breeds, identifying key genetic markers that could enhance breeding efficiency.

This study observed that 2.5% of patients with mycosis fungoides or Szary syndrome experienced alopecia, predominantly within skin lesions, with scalp metastases from other cancers also potentially causing hair loss, highlighting the diagnostic value of trichoscopy in differentiating alopecia types.

This study developed microneedles combining insulin-like growth factor-1 and type XVII collagen, showing more effective hair regeneration and reduced inflammation compared to minoxidil in a mouse model of androgenetic alopecia.