Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

The conclusion suggests a new treatment for infantile hemangiomas and a potential target for hair loss treatment.

This study found that VEGF, produced by human dermal papilla cells, can promote hair growth in vitro without increasing the proliferation of dermal papilla cells.

This study described the safety profile of tyrosine kinase inhibitors in treating various solid tumors, finding that the observed toxicities were consistent with existing literature.

This article organizes and lists ongoing and completed clinical trials of novel agents for lung cancer, serving as a reference tool with no new research findings reported.

This study identified critical roles for the gene GREM1 in the differentiation and expansion of endothelial progenitors derived from human urinary induced pluripotent stem cells.

In this study, researchers observed that blood vessel maturation in mice involves neonatal endothelial cells expanding the capillary network through vessel regression and angiogenesis, with adult cells later maintaining stability and repair through specific signaling pathways.

This Phase II study found that BAY 43-9006, given at 400 mg orally twice daily, led to stable disease in 30% and tumor reduction in 40% of renal cell carcinoma patients.

The document concludes that various medications and treatments can have significant, sometimes adverse, effects on health outcomes.

This study concluded that using human umbilical cord blood mononuclear cells transfected with VEGF and FGF2 genes enhances skin wound healing in rats, demonstrating greater wound revascularization compared to controls.

This study found that urotensin II promoted proliferation and VEGF secretion in rat dermal papilla cells by activating the Wnt-β-catenin signaling pathway, with the effect being reversible by a Wnt inhibitor.

This study found that VEGF-deficient keratinocytes can form tumors using different aneuploidy and signaling patterns, highlighting VEGF's role beyond angiogenesis in tumor cell growth and survival.

Fgfr2b helps maintain healthy skin and prevent cancer.

Mast cells and VEGF contribute to post-surgery adhesions, and blocking VEGF can reduce these adhesions; also, certain factors affect wound healing and fetal skin heals differently with age.

The researchers reported that VEGF increases vascular permeability in mesenteric microvessels of anaesthetized frogs through specific cellular pathways involving tyrosine autophosphorylation and PLC activation.

This study found that transgenic mice expressing cgVEGF164 had increased hair follicle diameter and density, potentially linked to higher phosphorylation levels of ERK1/2, AKT1, and LEF1 proteins.

In this study, immobilized VEGF selectively captured endothelial cells under various shear stresses, suggesting its potential for promoting endothelialization in vascular grafts or implanted tissues.

In a mouse model of chemotherapy-induced alopecia, this study found that enhancing ETV2 expression improved angiogenesis and hair regrowth following 5-fluorouracil treatment.

This study found that VEGF significantly promoted hair follicle growth and regeneration in mice with scleroderma.

mTORC2 is crucial for healthy skin barrier by regulating lipids and filaggrin.

This study found that rat hair follicle stem cells can be effectively transfected with VEGF 165 using lentivirus vectors, suggesting their potential use in developing tissue-engineered skin with improved vascularization.

This study observed that thymosin beta 4 and VEGF have similar expression patterns in various human tissues, suggesting a role in angiogenesis and organ function.

In this study, mice engineered to express human EGFR showed tissue-specific growth defects and neurodegeneration rescue, but developed severe heart issues and accelerated bone cell differentiation.

This article reviews the role of VEGF in hair follicle growth and cycle modulation but concludes that its specific molecular mechanisms in hair follicle growth remain unclear.

This study found that epidermal VEGF is crucial for maintaining skin barrier function in mice and may help explain psoriasis development following skin trauma due to its effects on angiogenesis and hyperplasia.

This study found that endothelial TLR2 is crucial for effective angiogenesis and timely wound healing, whereas TLR2 in hair follicle stem cells is not essential for skin regeneration.

This study found that treating mouse epidermal neural crest stem cells with EGF and FGF2 increased their proliferation and enhanced their neuronal differentiation potential.

The researchers in this study identified a new subpopulation of dermal fibroblasts in neonatal murine dermis marked by EGFR, which they report contributes to hair follicle regeneration through the promotion of IGF1, potentially aiding in wound-induced hair follicle neogenesis.

This study found that EP 2 signaling is crucial for macrophage recruitment and inflammatory regulation in the injured heart, impacting cardiac repair processes.