Mechanisms of Vascular Maturation and Maintenance Captured by Longitudinal Imaging of Live Mouse Skin

    Chen Yuan Kam, I. Singh, Catherine Matte-Martone, David G. Gonzalez, Paloma Solá, Guiomar Solanas, Júlia Bonjoch, Edward Marsh, Karen K. Hirschi, Valentina Greco

    Preprint — not peer reviewed. This was posted to a preprint server or data repository. It has not been through a journal's review process, and its findings may change or not hold up.

    Studysummary In this study, researchers observed that blood vessel maturation in mice involves neonatal endothelial cells expanding the capillary network through vessel regression and angiogenesis, with adult cells later maintaining stability and repair through specific signaling pathways.
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