Intravital Imaging of Hair Follicle Regeneration in the Mouse

    June 2015 in “ Nature Protocols ”
    Cristiana M. Pineda, Sang-Bum Park, Kailin R. Mesa … Valentina Greco
    Studysummary This protocol describes using two-photon laser-scanning microscopy to study hair regeneration in live mice, offering detailed imaging capabilities for observing hair follicle stem cell behavior and manipulating cellular populations.
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    Research cited in this study 5

    1. Stem Cell Dynamics in the Hair Follicle Niche Seminars in Cell & Developmental Biology · 2013
    2. Spatial Organization Within a Niche as a Determinant of Stem-Cell Fate Nature · 2013
    3. Identification of the Cell Lineage at the Origin of Basal Cell Carcinoma Nature Cell Biology · 2010
    4. Coexistence of Quiescent and Active Adult Stem Cells in Mammals Science · 2010
    5. Molecular Dissection of Mesenchymal–Epithelial Interactions in the Hair Follicle PLoS biology · 2005

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    3. Live Imaging of Stem Cell and Progeny Behavior in Physiological Hair-Follicle Regeneration Nature · 2012
    4. Coordinated Activation of Wnt in Epithelial and Melanocyte Stem Cells Initiates Pigmented Hair Regeneration Cell · 2011
    5. Skin and Hair: Models for Exploring Organ Regeneration Human Molecular Genetics · 2008