Search
for

    Glossary Tumor Suppressor Protein

    prevents uncontrolled cell growth and tumor formation

    A Tumor Suppressor Protein is a type of protein that helps regulate cell growth and division, preventing cells from growing uncontrollably and forming tumors. These proteins, often produced by tumor suppressor genes, act as the body's natural defense against cancer by repairing DNA damage or initiating cell death if the damage is irreparable.

    Related Terms

    Sort by

    Research 30 of 1000+

    1. The human promyelocytic leukemia protein is a tumor suppressor for murine skin carcinogenesis Molecular Carcinogenesis · 2008 · 10 citations
    2. Folliculin, the Product of the Birt-Hogg-Dube Tumor Suppressor Gene, Interacts with the Adherens Junction Protein p0071 to Regulate Cell-Cell Adhesion PloS one · 2012 · 72 citations
    3. The secret identities of TMPRSS2: Fertility factor, virus trafficker, inflammation moderator, prostate protector and tumor suppressor Tumor Biology · 2021 · 16 citations
    4. Grp1-associated scaffold protein regulates skin homeostasis after ultraviolet irradiation Photochemical & photobiological sciences · 2014 · 2 citations
    5. A Nonredundant Human Protein Chip for Antibody Screening and Serum Profiling Molecular & cellular proteomics · 2003 · 117 citations
    6. Human hair proteins as natural reactive oxygen species scavengers for in vitro applications Journal of biomedical materials research. Part B, Applied biomaterials · 2022 · 4 citations
    7. Role of the bone morphogenetic protein signalling in skin carcinogenesis. Effect of transgenic overexpression of BMP antognist Noggin on skin tumour development; molecular mechanisms underlying tumour suppressive role of the BMP signalling in skin. Bradford Scholars (University of Bradford) · 2009
    8. A new way to restore tumour suppressor function Nature Reviews Drug Discovery · 2013
    9. Single-cell analysis of basal cell carcinoma reveals heat shock proteins promote tumor growth in response to WNT5A-mediated inflammatory signals bioRxiv (Cold Spring Harbor Laboratory) · 2021 · 1 citations
    10. The Double-Edged Proteins in Cancer Proteomes and the Generation of Induced Tumor-Suppressing Cells (iTSCs) Proteomes · 2023 · 4 citations
    11. The Paradox of p53: What, How, and Why? Cold Spring Harbor Perspectives in Medicine · 2016 · 64 citations
    12. Apoptosis and cutaneous biology Journal of The American Academy of Dermatology · 1997 · 60 citations
    13. Epigenetic regulation in adult stem cells and cancers Cell & Bioscience · 2013 · 20 citations
    14. p53 Is a Direct Transcriptional Repressor of Keratin 17: Lessons from a Rat Model of Radiation Dermatitis Journal of Investigative Dermatology · 2015 · 19 citations
    15. Targeting the Hippo/YAP/TAZ signalling pathway: Novel opportunities for therapeutic interventions into skin cancers Experimental dermatology · 2022 · 7 citations
    16. CXXC5: A novel regulator and coordinator of TGF-β, BMP and Wnt signaling Journal of Cellular and Molecular Medicine · 2018 · 28 citations
    17. Skin Cancer: Mechanisms and Human Relevance Medical Entomology and Zoology · 1994 · 213 citations
    18. Human tissue kallikreins as promiscuous modulators of homeostatic skin barrier functions Biological Chemistry · 2008 · 84 citations
    19. A Case of Virilizing Brenner Tumor in a Postmenopausal Woman With Stromal Androgenic Activity International Journal of Gynecological Pathology · 2006 · 6 citations
    20. Impaired Keratinocyte Proliferative and Clonogenic Potential in Transgenic Mice Overexpressing 14-3-3σ in the Epidermis Journal of Investigative Dermatology · 2011 · 15 citations
    21. Reduced SMAD2/3 activation independently predicts increased depth of human cutaneous squamous cell carcinoma Oncotarget · 2018 · 11 citations
    22. Cylindroma as Tumor of Hair Follicle Origin Journal of Investigative Dermatology · 2006 · 57 citations
    23. Human Placenta Extract (HPH) Suppresses Inflammatory Responses in TNF-α/IFN-γ-Stimulated HaCaT Cells and a DNCB Atopic Dermatitis (AD)-Like Mouse Model Journal of Microbiology and Biotechnology · 2024 · 3 citations
    24. Bone Morphogenetic Protein Antagonist Noggin Promotes Skin Tumorigenesis via Stimulation of the Wnt and Shh Signaling Pathways American Journal Of Pathology · 2009 · 45 citations
    25. Folliculin encoded by the <i>BHD</i> gene interacts with a binding protein, FNIP1, and AMPK, and is involved in AMPK and mTOR signaling Proceedings of the National Academy of Sciences · 2006 · 475 citations
    26. Inhibition of the development of metastatic squamous cell carcinoma in protein kinase C epsilon transgenic mice by alpha-difluoromethylornithine accompanied by marked hair follicle degeneration and hair loss. PubMed · 2003 · 26 citations
    27. 17β-estradiol Inhibits the Production of RANTES in Human Keratinocytes Journal of Investigative Dermatology · 2003 · 56 citations
    28. Divergent roles of HDAC1 and HDAC2 in the regulation of epidermal development and tumorigenesis The EMBO Journal · 2013 · 65 citations
    29. Folliculin interacts with p0071 (plakophilin-4) and deficiency is associated with disordered RhoA signalling, epithelial polarization and cytokinesis 2012 · 47 citations
    30. Signal Peptide-CUB-EGF-like Domain-Containing Protein 3 (SCUBE3): From Molecule to Therapy Therapeutics · 2026