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    GlossaryCell cycle inhibitor (Cell cycle regulator)

    molecule that halts or slows down cell division

    A cell cycle inhibitor, also known as a cell cycle suppressor or cell cycle regulator, is a molecule that can halt or slow down the process of cell division. These inhibitors play a crucial role in controlling cell growth and ensuring that cells do not divide uncontrollably, which is important for preventing conditions like cancer. For example, proteins like p21 and p27 are well-known cell cycle inhibitors that can stop the cell cycle at specific checkpoints, allowing for DNA repair or triggering cell death if the damage is irreparable.

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      learn Rapamycin

      mTOR regulator and immunosuppressant used more recently for anti-aging and hair regrowth

      learn Procyanidin

      bioflavonoid found in plants with antioxidant and hair stimulating properties

      learn PP405

      mitochondrial pyruvate carrier (MPC) inhibitor by Pelage in early trials

      learn Estradiol

      an estrogen promoting hair regrowth more commonly used in women

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      community New and Interesting HairLoss Studies/Papers/Reviews

      in Treatment  42 upvotes 4 years ago
      Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.

      community Got a microscope camera. Here’s the difference between healthy and miniaturized hair

      in Progress Pictures  492 upvotes 2 years ago
      A user who shared progress pictures of their scalp using a microscope camera, demonstrating the difference between healthy and miniaturized hair. Various explanations for the cause of this were discussed, such as DHT build-up in scalp sebum causing an autoimmune response leading to inflammation and eventual hair loss, with some suggesting a do-it-yourself treatment involving adding ascorbic acid powder to shampoo.

      community Fats on your Head to Stop Hair Loss?

      in Research/Science  141 upvotes 9 months ago
      The conversation discusses the potential of long-chain unsaturated fatty acids, like oleic and linoleic acid, as an additional treatment for hair loss, which may inhibit the enzyme responsible for converting testosterone to DHT and promote hair growth. Users humorously suggest using oils topically and discuss other hair loss treatments, but the main focus is on the science behind fatty acids and their role in hair health.