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    Glossary Myeloid-Derived Suppressor Cells

    immune cells from bone marrow that suppress immune responses

    Myeloid-Derived Suppressor Cells (MDSCs) are a type of immune cell that originates from bone marrow and has the ability to suppress the body's immune response. They play a significant role in cancer and other diseases by inhibiting the activity of T cells and natural killer cells, which can allow tumors to grow and spread more easily.

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    1. The Importance of Myeloid-Derived Suppressor Cells in the Regulation of Autoimmune Effector Cells by a Chronic Contact Eczema The Journal of Immunology · 2007 · 84 citations
    2. Immunoregulatory Effects of Myeloid-Derived Suppressor Cell Exosomes in Mouse Model of Autoimmune Alopecia Areata Frontiers in immunology · 2018 · 45 citations
    3. Finasteride Enhances the Generation of Human Myeloid-Derived Suppressor Cells by Up-Regulating the COX2/PGE2 Pathway PLOS ONE · 2016 · 10 citations
    4. 413 DC-HIL+ myeloid-derived suppressor cells are elevated in the peripheral blood and lesional skin of cutaneous lupus patients Journal of Investigative Dermatology · 2018
    5. Attending persistent T cell activation in alopecia areata : A therapeutic option Repository KITopen (Karlsruhe Institute of Technology) · 2011
    6. Single-cell analysis reveals fibroblast heterogeneity and myeloid-derived adipocyte progenitors in murine skin wounds Nature Communications · 2019 · 301 citations
    7. UTMD Enhances Targeting of Diclofenac and Doxil® to Boost Tumor Immunotherapy Ultrasound in Medicine & Biology · 2025
    8. Clinical perspectives on the age-related increase of immunosuppressive activity Journal of Molecular Medicine · 2022 · 55 citations
    9. 415 IL-17C: Checkpoint in innate skin immunology Journal of Investigative Dermatology · 2018
    10. Metformin and Malignant Tumors: Not Over the Hill Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy · 2021 · 14 citations
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