84 citations
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October 2007 in “The Journal of Immunology” This study found that chronic eczema supports the expansion of myeloid suppressor cells, which contribute to silencing autoreactive T cells and partially promote hair regrowth in alopecia areata.
45 citations
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June 2018 in “Frontiers in immunology” This study found that MDSC exosomes promoted partial hair regrowth and modulated immune responses in mice with alopecia areata, suggesting potential as a treatment for autoimmune diseases.
10 citations
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June 2016 in “PLOS ONE” In this in-vitro study, researchers identified finasteride as the most effective FDA-approved drug for expanding functional myeloid-derived suppressor cells, suggesting its potential future use in immunosuppressive therapies.
April 2018 in “Journal of Investigative Dermatology” This study found that DC-HIL+ myeloid derived suppressor cells are increased in the blood and skin of patients with cutaneous lupus erythematosus and show immunosuppressive properties.
January 2011 in “Repository KITopen (Karlsruhe Institute of Technology)” This study suggests that contact sensitizers may treat alopecia areata by expanding suppressor cells and interfering with antigen presentation to lymphocytes.