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GlossaryImatinib

targets specific enzymes to treat certain cancers like CML

Imatinib, also known as Gleevec, is a targeted cancer therapy drug used primarily to treat chronic myeloid leukemia (CML) and gastrointestinal stromal tumors (GISTs). It works by inhibiting specific tyrosine kinases, which are enzymes that promote the growth of cancer cells, thereby slowing or stopping the progression of the disease.

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Hair Graying and Loss Induced by Imatinib Mesylate

research Hair Graying and Loss Induced by Imatinib Mesylate

7 citations, December 2013 in “The Journal of Dermatology”

A woman's hair turned gray and fell out after starting a cancer drug called imatinib mesylate.

research Imatinib-Induced Classical Lichen Planopilaris in Blaschko-Linear Distribution Leading to Cicatricial Alopecia

2 citations, February 2021 in “Indian Dermatology Online Journal”

Imatinib can cause hair loss due to lichen planopilaris.

research Keratosis Pilaris-Like Eruption During Chronic Myeloid Leukemia Treatment With Tyrosine Kinase Inhibitors: A Literature Review And Case Report On Imatinib

December 2023 in “Journal of clinical medicine”

Some leukemia treatments can cause skin reactions similar to keratosis pilaris.

research Author Reply

1 citations, April 2004 in “Cancer”

Imatinib mesylate can cause skin lightening, especially in Chinese patients, due to its effect on pigment production.

research Tyrosine Kinase Inhibitors: A Review on Pharmacology, Metabolism, and Side Effects

508 citations, June 2009 in “Current drug metabolism”

Tyrosine kinase inhibitors effectively treat cancers but often cause skin and other side effects.

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