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GlossaryDasatinib

medication used to treat certain types of leukemia

Dasatinib is a medication primarily used to treat certain types of leukemia, a cancer of the blood cells. It works by inhibiting specific proteins that promote the growth of cancer cells, thereby slowing or stopping their proliferation. For professionals, it's known as a tyrosine kinase inhibitor and is effective against chronic myeloid leukemia (CML) and acute lymphoblastic leukemia (ALL) with the Philadelphia chromosome.

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Adverse Cutaneous Reactions to the New Second-Generation Tyrosine Kinase Inhibitors (Dasatinib, Nilotinib) in Chronic Myeloid Leukemia

research Adverse Cutaneous Reactions to the New Second-Generation Tyrosine Kinase Inhibitors (Dasatinib, Nilotinib) in Chronic Myeloid Leukemia

25 citations , November 2013 in “Journal of the American Academy of Dermatology”

Many patients on new leukemia drugs had mild to moderate skin reactions.

research Dasatinib-Induced Leukotrichia in a Patient With Chronic Myelogenous Leukemia

9 citations , May 2013 in “JAMA Dermatology”

A woman's hair turned white after taking a cancer drug called dasatinib.

research Tyrosine Kinase Inhibitors: A Review on Pharmacology, Metabolism, and Side Effects

508 citations , June 2009 in “Current drug metabolism”

Tyrosine kinase inhibitors effectively treat cancers but often cause skin and other side effects.

research Unique Cutaneous Reaction to Second- and Third-Generation Tyrosine Kinase Inhibitors for Chronic Myeloid Leukemia

32 citations , September 2015 in “Dermatology”

Certain leukemia drugs can cause severe skin reactions that may require stopping treatment.

research Flexural Agminated Eruptive Nevi in Langerhans Cell Histiocytosis

9 citations , May 2013 in “JAMA Dermatology”

Sunlight exposure improved a patient's skin condition, and there may be a link between a certain disease and skin growths; a leukemia treatment caused changes in hair color and growth.

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