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    Glossary Tumor Protein p63

    protein crucial for epithelial tissue development and maintenance

    Tumor Protein p63 (often referred to as p63 or TP63) is a protein that plays a crucial role in the development and maintenance of epithelial tissues, which are the layers of cells covering surfaces and lining cavities in the body. It is involved in regulating cell proliferation, differentiation, and apoptosis (programmed cell death). Mutations in the TP63 gene can lead to various developmental disorders and have been linked to certain types of cancer.

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    1. The Paradox of p53: What, How, and Why? Cold Spring Harbor Perspectives in Medicine · 2016 · 64 citations
    2. Mechanism of TAp73 inhibition by ΔNp63 and structural basis of p63/p73 hetero-tetramerization Cell death and differentiation · 2016 · 29 citations
    3. S100A6 Protein—Expression and Function in Norm and Pathology International Journal of Molecular Sciences · 2023 · 21 citations
    4. 1435 Dynamic morphogen-p63 chromatin interactions that guide epigenetic changes and p63 activity in surface ectoderm commitment Journal of Investigative Dermatology · 2018
    5. p53 Is a Direct Transcriptional Repressor of Keratin 17: Lessons from a Rat Model of Radiation Dermatitis Journal of Investigative Dermatology · 2015 · 19 citations
    6. Targeting the Hippo/YAP/TAZ signalling pathway: Novel opportunities for therapeutic interventions into skin cancers Experimental dermatology · 2022 · 7 citations
    7. Keratin K15 as a Biomarker of Epidermal Stem Cells International Journal of Molecular Sciences · 2013 · 85 citations
    8. The Role of ATP-dependent Chromatin Remodeling in the Control of Epidermal Differentiation and Skin Stem Cell Activity Stem cell biology and regenerative medicine · 2018
    9. Differential Regulation of Vitamin D Receptor (VDR) By P53, P63 and P73 OhioLink ETD Center (Ohio Library and Information Network) · 2009
    10. RAGE and Its Ligands in Melanoma InTech eBooks · 2015 · 1 citations
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