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GlossaryMatrigel

gelatinous protein mixture used to simulate cellular environments

Matrigel is a gelatinous protein mixture derived from mouse tumor cells, commonly used in biological research to simulate the environment around cells. It provides a scaffold that supports cell growth and differentiation, making it particularly useful for studying cell behavior, tissue engineering, and drug testing.

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research Controllable Production of Transplantable Adult Human High-Passage Dermal Papilla Spheroids Using 3D Matrigel Culture

46 citations, September 2014 in “Tissue engineering. Part A”

Researchers created hair-inducing human cell clusters using a 3D culture method.

research Self-Assembled Complete Hair Follicle Organoids by Coculture of Neonatal Mouse Epidermal Cells and Dermal Cells in Matrigel

4 citations, July 2022 in “Annals of translational medicine”

Scientists created complete hair-like structures by growing mouse skin cells together in a special gel.

research Culture of Pyramidal Neural Precursors, Neural Stem Cells, and Fibroblasts on Various Biomaterials

3 citations, September 2018 in “Journal of Biomaterials Science, Polymer Edition”

Different materials affect the growth of brain cells and fibroblasts, with matrigel being best for brain cell growth.

research Towards Expansion of Human Hair Follicle Stem Cells In Vitro

14 citations, April 2011 in “Cell Proliferation”

Scientists can grow human hair follicle stem cells in a lab without changing their nature, which could help treat hair loss.

research Biofabrication of Human Skin with Its Appendages

10 citations, September 2022 in “Advanced Healthcare Materials”

Current methods can't fully recreate skin and its features, and more research is needed for clinical use.

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