402 citations,
August 2011 in “Cancer research” Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.
181 citations,
February 2019 in “Cell” Innate lymphoid cells help control skin bacteria by regulating sebaceous glands.
129 citations,
July 2019 in “Stem Cell Research & Therapy” Epidermal stem cells help heal severe skin wounds and have potential for medical treatments.
71 citations,
September 2006 in “Cell Transplantation” Fetal skin cells from a cell bank heal wounds faster and with less scarring than adult cells.
67 citations,
June 2019 in “Proceedings of the National Academy of Sciences” A new 3D culture system helps grow and study mouse skin stem cells for a long time.
41 citations,
March 2019 in “Circulation research” Adult stem cells are effective and ethically acceptable for treating various diseases.
37 citations,
April 2017 in “npj Regenerative Medicine” PDGF signaling is crucial for maintaining and renewing hair follicle stem cells, which could help treat hair loss.
35 citations,
January 2020 in “Skin Pharmacology and Physiology” The review concluded that keeping the hair-growing ability of human dermal papilla cells is key for hair development and growth.
33 citations,
January 2018 in “Blood” Ruxolitinib helps protect skin stem cells and keeps skin healthy in mice with skin GVHD.
33 citations,
October 2013 in “PloS one” Human sweat glands have a type of stem cell that can grow well and turn into different cell types.
21 citations,
May 2018 in “Journal of Cosmetic Dermatology” Costunolide helps human hair cells grow and can stimulate hair growth in mice.
17 citations,
May 2014 in “Cell transplantation” Genetically modified stem cells from human hair follicles can lower blood sugar and increase survival in diabetic mice.
14 citations,
January 2019 in “Advances in experimental medicine and biology” Skin stem cells are promising for healing wounds and skin regeneration due to their accessibility and regenerative abilities.
9 citations,
January 2017 in “Elsevier eBooks” Skin's epithelial stem cells are crucial for repair and maintenance, and understanding them could improve treatments for skin problems.
6 citations,
July 2016 in “Cell cycle/Cell cycle (Georgetown, Tex. Online)” Younger mice's hair-follicle stem cells are better at turning into heart cells than older mice's.
5 citations,
October 2020 in “Frontiers in Cell and Developmental Biology” Reducing FOXA2 in skin cells lowers their ability to grow hair.
5 citations,
March 2017 in “Cell and Tissue Banking” Researchers developed a new method to quickly prepare skin cells that improve wound healing in rats.
3 citations,
October 2023 in “Military Medical Research/Military medical research” Regulatory T cells help heal skin and grow hair, and their absence can lead to healing issues and hair loss.
3 citations,
May 2022 in “Oncogene” Vav2 and Vav3 proteins help control skin stem cell numbers and activity in both healthy and cancerous cells.
3 citations,
April 2022 in “International Journal of Molecular Sciences” Scientists turned mouse skin cells into hair-inducing cells using chemicals, which could help treat hair loss.
3 citations,
May 2008 in “Hair transplant forum international” Common hair loss disorders may not need stem cell therapy, but could benefit from other treatments like hair cycle control and immune restoration therapy.
1 citations,
September 2023 in “Stem cell research & therapy” Mesenchymal stem cells could help treat aging-related diseases better than current methods.
1 citations,
January 2023 in “International Journal of Molecular Sciences” Understanding how Regulatory T Cells work could help create treatments for certain skin diseases and cancers.
March 2024 in “Biomedicines” Mesenchymal stem cells show promise for effective skin repair and regeneration.
August 2023 in “Journal of Cosmetic Dermatology” Exosomes from hair papilla cells and the Chinese medicine Liao Tuo Fang can potentially promote hair growth and could be used to develop hair growth drugs.
Certain natural products may help stimulate hair growth by affecting stem cell activity in the scalp.
May 2022 in “Research Square (Research Square)” Nestin marks cells that can become a specific type of skin cell in hair follicles of both developing and adult mice.
The natural compound VB-1, found in a Chinese herb, can promote hair growth by boosting cell activity in human skin cells.
VB-1, a natural compound, may promote hair growth by enhancing important cell signaling and increasing key gene expression.
April 2018 in “Journal of Investigative Dermatology” Different types of stem cells in the skin contribute to the variety of melanoma forms.