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Glossary3D Structures (Three-Dimensional Structures)

represent objects with length, width, and depth in space

3D Structures, or Three-Dimensional Structures, refer to objects or models that have length, width, and depth, providing a realistic representation of their form in space. In the context of biology and hair, 3D structures can be used to visualize the intricate architecture of hair follicles, proteins, or other cellular components, aiding in the understanding of their function and interactions, which is crucial for research into conditions like alopecia.

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research Biomimetic Scaffolds: A Novel Approach to Three-Dimensional Cell Culture Techniques for Potential Implementation in Tissue Engineering

1 citations, March 2024 in “Nanomaterials”

Biomimetic scaffolds are better than traditional methods for growing cells and could help regenerate various tissues.

research Synergistic Effect of Carbodiimide and Dehydrothermal Crosslinking on Acellular Dermal Matrix

61 citations, January 2013 in “International Journal of Biological Macromolecules”

Combining DHT and EDC improves the strength and stability of PADM scaffolds for tissue engineering.

High-Resolution Structures of Mutants Affecting Access to the Ligand-Binding Cavity of Human Lipocalin-Type Prostaglandin D Synthase

research High-Resolution Structures of Mutants Affecting Access to the Ligand-Binding Cavity of Human Lipocalin-Type Prostaglandin D Synthase

5 citations, July 2014 in “Acta Crystallographica Section D-biological Crystallography”

Mutations in the enzyme don't significantly change how it binds to its specific substances.

research Molecular Docking Study of Phytochemical Compounds from Kushtakudori Ennai as a Potential Anti-Alopecia Treatment

July 2024 in “International Journal of Ayurvedic Medicine”

Certain compounds from Kushtakudori ennai may help treat hair loss.

research A Compositionally Synergistic Approach for the Development of a Multifunctional Bilayer Scaffold with Antibacterial Property for Infected and Chronic Wounds

54 citations, May 2021 in “Chemical Engineering Journal”

The developed scaffold effectively treats chronic wounds by promoting healing and preventing infection.

research Roles of Steroid Sulfatase in Brain and Other Tissues

22 citations, January 2008 in “Physiological Research”

Steroid sulfatase is important for activating hormones that affect memory, brain function, and certain diseases, and could be a target for treating hormone-related disorders.

research Sulfotransferases, Sulfatases, and Formylglycine-Generating Enzymes: A Sulfation Fascination

83 citations, July 2008 in “Current Opinion in Chemical Biology”

The document concludes that understanding sulfation biology is crucial for creating treatments due to its importance in biological functions and disease.

research In Silico Prediction of Prostaglandin D2 Synthase Inhibitors from Herbal Constituents for the Treatment of Hair Loss

30 citations, October 2015 in “Journal of Ethnopharmacology”

Herbal compounds like ricinoleic acid, quercetin-3-O-rutinoside, and hinokiflavone may be safe and effective for treating hair loss.

research Effect of Varied Hair Protein Fractions on the Gel Properties of Keratin/Chitosan Hydrogels for Use in Tissue Engineering

41 citations, November 2020 in “Colloids and surfaces. B, Biointerfaces”

Different hair protein amounts change the strength of keratin/chitosan gels, useful for making predictable tissue engineering materials.

research Wound Regeneration Deficit in Rats Correlates with Low Morphogenetic Potential and Distinct Transcriptome Profile of Epidermis

21 citations, January 2018 in “Journal of Investigative Dermatology”

Rats can't grow new hair follicles after skin wounds, unlike mice, due to differences in gene expression and response to WNT signaling.

research Skipping of Exons by Premature Termination of Transcription and Alternative Splicing Within Intron-5 of the Sheep SCF Gene: A Novel Splice Variant

6 citations, June 2012 in “PloS one”

A new mRNA variant of the SCF gene in sheep skin produces a shorter, different protein.

research Potential Medical Uses of Cannabigerol: A Brief Overview

14 citations, January 2017 in “Elsevier eBooks”

CBG may help with various medical conditions but needs more human research to confirm safety and effectiveness.

research Genetic Screening of Non-Classic CAH Females with Hyperandrogenemia Identifies a Novel CYP11B1 Gene Mutation

April 2016 in “Hormones”

A new mutation in the CYP11B1 gene was found in a woman with mild hyperandrogenemia, a rare cause of non-classic congenital adrenal hyperplasia.

research Synthesis, Anticancer, and Molecular Docking Studies of 2-(4-Chlorophenyl)-5-Aryl-1,3,4-Oxadiazole Analogues

8 citations, January 2013 in “Medicinal chemistry”

The compound 4c showed strong potential as an anticancer agent.

research Poly (ɛ-Caprolactone)–Chitosan–Poly (Vinyl Alcohol) Nanofibrous Scaffolds for Skin Excisional and Burn Wounds in a Canine Model

11 citations, January 2018 in “IET Nanobiotechnology”

The scaffolds significantly sped up wound healing in dogs and were safe.

research A Guide to the Use of Bioassays in Exploration of Natural Resources

January 2024 in “Biotechnology advances”

Bioassays help find useful compounds in nature for making medicines, supplements, and cosmetics.

research In Vitro Models to Study Hair Follicle Generation

5 citations, November 2017 in “Elsevier eBooks”

Scientists can now grow hair-like structures in a lab using special 3D culture systems, which could potentially help people with hair loss or severe burns.

research Validity and Advantages of Three-Dimensional High-Frequency Ultrasound in Dermatological Evaluation

January 2025 in “Diagnostics”

3D high-frequency ultrasound can help diagnose skin and hair conditions without invasive biopsies.

Three-Dimensional Imaging of Tight Junction Network Across Multiple Layers of Human Epidermis by Array Tomography Using Backscattered Electron-Mode Scanning Electron Microscopy

research Three-Dimensional Imaging of Tight Junction Network Across Multiple Layers of Human Epidermis by Array Tomography Using Backscattered Electron-Mode Scanning Electron Microscopy

August 2019 in “Journal of Investigative Dermatology”

The study found that tight junctions reach the top layer of the skin's stratum granulosum, not just the second top layer as previously thought.

research Three-Dimensional Reconstructions of Mechanosensory End Organs Suggest a Unifying Mechanism Underlying Dynamic, Light Touch

5 citations, March 2023 in “bioRxiv (Cold Spring Harbor Laboratory)”

Dynamic, light touch is sensed through a common mechanism involving Piezo2 channels in sensory axons.

research Biofabrication Technologies in Hair Neoformation

January 2022 in “Stem cell biology and regenerative medicine”

New biofabrication technologies could lead to treatments for hair loss.

research Fabrication and Characterization of Epithelial Scaffolds for Hair Follicle Regeneration

4 citations, May 2012 in “Tissue Engineering and Regenerative Medicine”

Scientists created three types of structures to help regrow hair follicles, and all showed promising results for hair regeneration.

research Pharmacophore Modeling and Three Dimensional Database Searching for Drug Design Using Catalyst: Recent Advances

153 citations, November 2004 in “Current Medicinal Chemistry”

The document concludes that Catalyst software is effective for drug design, identifying potent compounds for various medical conditions.

research Therapeutic Effect of a Xeno-Free Three-Dimensional Stem Cell Mass in a Hind Limb Ischemia Model

2 citations, September 2018 in “Tissue Engineering Part A”

Xeno-free three-dimensional stem cell masses are safe and effective for improving blood flow and tissue repair in limb ischemia.

research Stem Cells, Organoids and Their Applications for Human Diseases: Special Issue of BMB Reports in 2023

2 citations, December 2022 in “Journal of Biochemistry and Molecular Biology”

Organoids created from stem cells are used to model diseases, test drugs, and develop personalized and regenerative medicine.

Sweat Glands Shrink Upward With Aging, Causing Dermal Layer Defects Leading to Loss of Skin Elasticity and Wrinkling - Establishment of 3D Imaging Method for Skin Appendages

research Sweat Glands Shrink Upward With Aging, Causing Dermal Layer Defects Leading to Loss of Skin Elasticity and Wrinkling - Establishment of 3D Imaging Method for Skin Appendages

September 2017 in “Journal of Investigative Dermatology”

Aging causes sweat glands to shrink and move upward, leading to less elastic skin and more wrinkles.

research Biomedical Applications of Organoids in Genetic Diseases

December 2024 in “Medical Review”

Organoids help study and treat genetic diseases, offering personalized medicine and therapy testing.

research Release Systems Based on Self-Assembling RADA16-I Hydrogels With a Signal Sequence Which Improves Wound Healing Processes

1 citations, April 2023 in “Scientific Reports”

Self-assembling RADA16-I hydrogels with bioactive peptides significantly improve wound healing.

research Structural Characterization of Polymorphs and Molecular Complexes of Finasteride

17 citations, January 1999 in “Journal of Molecular Structure”

Finasteride's molecular and crystal structures help develop new drug formulations.

research Structure and Mechanical Properties of Human Trichocyte Keratin Intermediate Filament Protein

51 citations, September 2012 in “Biomacromolecules”

Disulfide bonds make keratin in hair stronger and tougher.