Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

In this mouse study, researchers found that orally administered low-molecular-weight fish collagen peptides significantly improved hair regrowth by both enhancing growth-promoting pathways and reducing inhibitory mechanisms.

Ganoderma lucidum extract may help treat stress-related hair loss.

This study suggests that enhancing glycolysis in MSCs may improve their immune functions and therapeutic potential, although more evidence is needed to understand the direct metabolic mechanisms involved.

This study highlights emerging research on lactate's biological roles in skin health, emphasizing its function as a signaling molecule that regulates skin barrier and immunity, and notes its therapeutic potential for skin conditions such as tumors and inflammatory diseases.

In this study, inducible whole-body Acly-knockout mice revealed that ACLY is essential for skin homeostasis, as its deficiency led to increased sebum production and skin abnormalities, indicating a vital role for cytosolic acetyl-CoA synthesis in preserving skin barrier integrity and systemic lipid regulation.

This study identified that copper depletion in dermal papilla cells reduced hair growth by boosting ROS levels, but ROS scavengers like NAC and ascorbic acid partially alleviated this effect.

In this study, researchers found that male and female APCHi mice exposed to ionizing radiation showed near-normal lipid and metabolite levels, suggesting activated protein C may offer some protective effects against radiation-induced damage affecting organ systems.

In this study, researchers found that 4-Octyl itaconate (4-OI) inhibited cisplatin-induced ferroptosis and protected auditory cells by activating the NRF2/HO-1 signaling pathway, suggesting a potential therapeutic approach for reducing hearing loss associated with cisplatin treatment.

This study found that the systemic wrinkled skin phenotype in Xiang pigs involves gene expression changes and genetic variations associated with oxidative stress and extracellular matrix components, resembling features seen in Shar-Pei dogs.

This study found that dietary serine levels influence hair follicle stem cells' ability to balance hair regeneration and wound repair, offering insights for potential interventions to accelerate wound healing.

This study found that in cashmere goats, melatonin treatments enhanced cashmere growth by stimulating secondary hair follicles, increasing follicle density, and improving yield and quality, highlighting key genes and metabolic pathways involved in this process.

This ex vivo study found that hair follicles in female pattern hair loss exhibited nutrient insufficiency and dormant metabolism, but maintained nutrient uptake capability, suggesting potential benefits of nutritional supplementation as an adjunct therapy.

This study found that Oncostatin M, via JAK-STAT5 signaling, keeps hair follicle stem cells inactive, and its removal leads to hair growth initiation in mice.

This study found that cedrol, administered orally, exhibited potential antiarthritic effects in rats by reducing inflammation, oxidative stress, and arthritis severity.

This study reported the development of new pyrazole-based MPC inhibitors that effectively inhibit mitochondrial pyruvate transport, showing potential as therapeutic candidates for conditions like metabolic dysfunction-associated steatohepatitis without activating PPARγ.

This review discusses the metabolic and physiological mechanisms that maintain hematopoietic stem cell function, particularly focusing on oxygen and energy homeostasis, but it reports no new experimental results.

This review highlights that unresolved inflammation is a major issue in diabetic foot ulcers and discusses emerging biomaterials-based strategies to modulate the inflammatory response, potentially aiding in tissue regeneration and healing in these chronic wounds.

This review explores the complex relationships between ferroptosis, anastasis, and chemoresistance in cancer therapy, highlighting the potential of combining ferroptosis with immunotherapy to overcome resistance and improve personalized cancer treatments.

This review explores how metabolic changes drive cellular quiescence and considers potential applications in cancer treatment by manipulating these processes.

In this study, copper was found to promote the proliferation of dermal papilla cells in Rex rabbits by maintaining the function of the cellular mitochondrial electron transport chain.

This review discusses the molecular mechanisms driving hair follicle degeneration in skin aging and emphasizes the role of the tissue microenvironment on stem cell function, but reports no new research findings.

This review explores the connection between oxidative stress and polycystic ovary syndrome, discussing potential mechanisms and the possible role of antioxidants; it reports no new clinical results.

This study found that α-ketoglutarate protected dermal papilla cells from oxidative stress by enhancing the Nrf2 pathway and mitigating cell damage through the ERK/Nrf2 axis.

This review discusses the role of hair follicle stem cell metabolism, ageing, and microenvironment in hair growth disorders and compiles recent research on using stem cell-based regenerative medicine for treating alopecia, without reporting new clinical results.

This review discusses the multifunctional role of PKM2 in promoting cardiac repair and regeneration, highlighting its potential as a therapeutic target in cardiovascular medicine, but reports no new experimental results.

This review summarizes current knowledge on succinic acid's applications in cosmetics and aesthetic dermatology, highlighting its potential benefits such as inflammation modulation and collagen production, although most supporting studies are small or preliminary, indicating a need for further research to validate these uses.

This review highlights the important role of the vitamin B complex in enhancing tissue repair, reducing inflammation, and improving surgical outcomes in plastic and reconstructive procedures by supporting cellular processes such as mitochondrial efficiency, neurotransmitter biosynthesis, and wound healing pathways.

This study investigated the genetic factors influencing cashmere quality differences between Jiangnan cashmere goats and Changthangi pashmina goats, identifying 4,942 differentially expressed genes and highlighting 24 key genes related to hair follicle development and cashmere fiber formation.

This study examined proteomic changes in Inner Mongolia cashmere goat skin, finding 631 proteins differentially regulated during hair growth stages; key keratin proteins, crucial for hair follicle development, were localized in secondary hair follicles.

This review summarizes current literature associating mitochondrial dysfunction with dermatologic issues like skin aging, hair loss, and poor wound healing, noting potential benefits in targeting mitochondrial components for treatments.