The Role of Metabolism in Cellular Quiescence

Cellular quiescence is a dormant state where cells do not divide, involving significant metabolic and physiological changes. This state is crucial for various biological processes such as microbial sporulation, human reproduction, and wound repair. Disruption in the regulation of quiescence can lead to cancer growth and hinder tissue regeneration. The review explores the metabolic changes that support quiescent cells, like spores, oocytes, and adult stem cells, and discusses how understanding these changes can aid in cancer treatment.