Is There a Histone Code for Cellular Quiescence?

    October 2021 in “ Frontiers in Cell and Developmental Biology ”
    Kenya Bonitto, Kirthana Sarathy, Kaiser Atai … Hilary A. Coller
    Studysummary This review discusses the role of histone marks in the transition between quiescence and proliferation in cells, and reports no new findings, emphasizing the potential existence of a histone "code" for quiescence.
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    Research cited in this study 6

    1. Histone H3 K4/9/27 Trimethylation Levels Affect Wound Healing and Stem Cell Dynamics in Adult Skin Stem Cell Reports · 2019
    2. Fibroblast Heterogeneity: Implications for Human Disease Journal of Clinical Investigation · 2018
    3. Signaling Couples Hair Follicle Stem Cell Quiescence With Reduced Histone H3 K4/K9/K27me3 for Proper Tissue Homeostasis Nature communications · 2016
    4. Genome-Wide Maps of Histone Modifications Unwind In Vivo Chromatin States of the Hair Follicle Lineage Cell stem cell · 2011
    5. Bald Scalp in Men with Androgenetic Alopecia Retains Hair Follicle Stem Cells but Lacks CD200-Rich and CD34-Positive Hair Follicle Progenitor Cells Journal of Clinical Investigation · 2011
    6. Coexistence of Quiescent and Active Adult Stem Cells in Mammals Science · 2010