Genome-Wide p63-Target Gene Analyses Reveal TAp63/NRF2-Dependent Oxidative Stress Responses

    January 2024 in “ Cancer Research Communications ”
    Marco Napoli, Avani A. Deshpande, Deepavali Chakravarti … Elsa R. Flores
    Studysummary This study found that TAp63 and ΔNp63 isoforms in the p63 family interact with different transcription factors to regulate distinct transcriptional programs, affecting various biological functions like metabolic pathways, oxidative stress response, and epithelial morphogenesis in mouse epidermal cells.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on aacrjournals.org →
    Discuss this study in the Community →

    Research cited in this study 1

    1. SKPs Derive from Hair Follicle Precursors and Exhibit Properties of Adult Dermal Stem Cells Cell stem cell · 2009