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Epidermal keratinocytes start wound healing and inflammation after schistosome infection.

Ifidancitinib, a JAK inhibitor, effectively regrows hair in mice with alopecia by tiring out harmful T cells.

Current and future treatments for alopecia areata focus on immunosuppression, immunomodulation, and protecting hair follicles.

Poor response to topical immunotherapy in alopecia areata patients is linked to impaired cell responses.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

Loss of a specific protein in skin cells causes symptoms similar to psoriasis.

Researchers found a specific immune receptor in patients that causes severe skin reactions to a drug.

Understanding the immune-related causes of Alopecia Areata has led to potential treatments like JAK inhibitors.

TNC+ fibroblasts play a key role in skin inflammation by interacting with T cells.

Cell therapy shows promise for treating severe psoriasis but needs more research to confirm safety and effectiveness.

Hair growth phase and certain genes can speed up wound healing, while an inflammatory mediator can slow down new hair growth after a wound. Understanding these factors can improve tissue regeneration during wound healing.

Malt1 protease is essential for regulatory T cell function and could be targeted to boost antitumor immunity.

FOXN1 is crucial for thymus development and immune response in Xenopus laevis.

Sebaceous glands play a key role in skin health, immunity, and various skin diseases.

Activating TLR9 helps heal wounds and regrow hair by using specific immune cells.

The reviewers suggest clarifying the abstract, adding background on inflammation's effect on stem cells and cancer, discussing immune cells' role in tumors, and considering inflammation's potential to reduce cancer growth.

Alopecia areata shows a unique type 1 interferon signature, suggesting potential treatment by targeting this pathway.

Immune checkpoint inhibitors can cause skin issues but are linked to better cancer outcomes.

The reviewers found the manuscript on inflammation's role in cancer stem cells to be relevant but suggested it needs clarity, more background information, discussion on immune cells' role in tumors, updated references, and grammar corrections.

Any drug can cause skin reactions, but antibiotics, NSAIDs, and psychotropic drugs are more common, with some reactions being life-threatening.

Alopecia areata is caused by immune system attacks on hair follicles, often triggered by viral infections.

Hair follicles are normally protected from the immune system, but when this protection fails, it can cause hair loss in alopecia areata.

Exosomes could be key in treating skin conditions and healing wounds.

Treg cell-based therapies might help treat hair loss from alopecia areata, but more research is needed to confirm safety and effectiveness.

Interferon, especially alfa interferon, is an effective treatment for cutaneous T-cell lymphoma with manageable side effects.

Mouse hair follicle stem cells can help prevent Type 1 Diabetes.

Reviewers suggest clarifying the abstract, adding background on inflammation's effect on cancer, discussing immune cell roles, including counter studies, and correcting grammar.

UV light helped human hair transplants survive in mice without broad immunosuppression.

The research confirms that Hidradenitis Suppurativa is characterized by increased inflammation, disrupted skin cell organization, and abnormal metabolic processes.

Using an anti-ICAM-1 antibody with rapamycin improves hair transplant survival in monkeys.