Inflammatory Auxo-Action in the Stem Cell Division Theory of Cancer
June 2023
TLDR The reviewers suggest clarifying the abstract, adding background on inflammation's effect on stem cells and cancer, discussing immune cells' role in tumors, and considering inflammation's potential to reduce cancer growth.
The document is a peer review of a manuscript discussing the role of inflammatory responses in the stem cell division theory of cancer. The initial submission had issues with clarity, repetition, and undefined abbreviations, but these were addressed in the revised version. The reviewers found the topic extensive and relevant. They suggested improvements such as revising the abstract for clarity, providing more background information on the effect of inflammatory responses on stem cells and cancer progression, discussing the role of different immune cells in tumor regulation, and including studies suggesting inflammation lowers cancer growth. They also recommended the inclusion of future studies and open questions to stimulate further research.