Inflammatory Responses in the Stem Cell Division Theory of Cancer

The document is a peer review of a study titled "The role of inflammatory responses in stem cell division theory of cancer". The initial manuscript had issues with clarity, repetition, and undefined abbreviations, but these were addressed in the revised version. The study explores the impact of inflammatory responses on cancer stem cell transition and progression. Reviewers found the topic extensive, relevant, and the manuscript well-structured. They appreciated the comprehensive literature review conducted by the authors. The reviewers suggested improvements such as revising the abstract for clarity, providing more background information on the effect of inflammatory responses on stem cells and cancer progression, discussing the role of different immune cells in regulating the tumor microenvironment, and including future studies and open questions to stimulate further research. Despite some initial issues, the manuscript was accepted in its revised format.