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High levels of male hormones, insulin resistance, and obesity are closely linked and worsen polycystic ovary syndrome, but more research is needed to improve treatments.

Finasteride doesn't affect bone density in male rats.

Finasteride caused enlarged breast tissue in a 62-year-old man.

Finasteride doesn't affect bone density in male rats.

The report concludes that PCOS is mainly a condition of excess male hormones and its definition may change as new information is discovered.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

DHT, a testosterone byproduct, causes male pattern baldness.

Using 5-alpha reductase inhibitors may increase the risk of mild depression.

Finasteride affects alcohol intake in male mice, possibly due to neurosteroids.

Hyperadrenocorticism in ferrets is linked to neutering and indoor housing, and is best treated with surgery and a deslorelin implant.

Certain gene variations are linked to a higher risk of severe acne, suggesting a genetic influence on the condition.

Fluridil promotes hair growth safely and effectively for androgenetic alopecia.

Understanding how DHT works is important for diagnosing and treating hormone-related disorders.

The document concludes that understanding sulfation biology is crucial for creating treatments due to its importance in biological functions and disease.

Neuroimaging suggests that treatments targeting brain steroids could help control epilepsy, especially types linked to the menstrual cycle.

The research found that measuring androgens in urine can give extra information about body metabolism and is linked to androgen levels in the blood, especially in young girls.

Omega-6 and LDL cholesterol increase the risk of hair loss.

Omega-6 fats in certain cells boost male hormone production.

Progesterone byproduct 5αP stimulates mammary tumor growth, but finasteride can suppress it.

Stress and alcohol affect brain chemicals differently in rats, mice, and humans, influenced by genetic differences.

New steroidal compounds could be effective for treating conditions related to 5α-reductase enzyme activity.

Finasteride treatment changes urine metabolomics and steroid signatures, potentially monitoring effectiveness but may cause sexual side effects.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

Different types of androgens bind differently to two receptors, AR1 and AR2, in Atlantic croaker's brain and ovarian tissues, suggesting these receptors may control different androgen actions in fish.

Testosterone replacement may help post-menopausal women with androgen insufficiency, but more research is needed on its benefits and risks.

Researchers developed a new method to find substances in herbs that can block a specific enzyme linked to hair loss.

A new compound effectively inhibits human 5α-reductase 1.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Plant steroid hormones show growth, health, and medicinal benefits in various organisms, including potential for treating diseases.

Steroid Sulfatase inhibitors show promise in treating hormone-dependent disorders like cancers, hair loss, and acne, with 667COUMATE being a potential candidate for breast cancer treatment trials.