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Gene differences may affect baldness treatment response in Korean men.

Compound 4 is a promising treatment for hair loss with low toxicity.

The enzyme 5α-reductase type 1 is important for blood vessel development and fertility in the uterus.

Men taking dutasteride or finasteride have a slightly higher risk of developing type 2 diabetes.

The enzyme 5α-reductase is important for proper blood vessel development during the fertility-related transformation of the uterus lining.

Four-amino acid part makes enzyme sensitive to finasteride.

Mice lacking steroid 5α-reductase 2 show less aggression and better impulse control.

LY320236 is a strong blocker of two enzymes that change testosterone into dihydrotestosterone and might help treat conditions related to male hormones.

Thai rice bran extracts, especially from Tubtim Chumphae rice, can significantly reduce the activity of hair loss genes, with x-tocopherol showing potential as an anti-hair loss product.

New steroidal compounds could be effective for treating conditions related to 5α-reductase enzyme activity.

Selective non-steroidal inhibitors of 5α-reductase type 1 can help treat DHT-related disorders.

Researchers developed a model to predict how well certain compounds can block an enzyme related to hair loss and prostate issues, suggesting a 50 mg dose of finasteride might be effective based on lab and body data.

PNU 157706 is a more effective treatment than finasteride for conditions caused by DHT, like enlarged prostate and hair loss.

New steroidal compounds moderately block an enzyme related to testosterone conversion, less effectively than finasteride.

FCE 28260 is a stronger and longer-lasting inhibitor of 5α-reductase than finasteride, which may make it a better treatment for certain medical conditions.

Researchers developed a new method to find substances in herbs that can block a specific enzyme linked to hair loss.

Rice bran extract might help prevent hair loss.

Natural herbal compounds might treat certain medical conditions by reducing DHT levels, but more research is needed to confirm their effectiveness and safety.

The new compounds moderately block a specific enzyme and strongly counteract a male hormone, suggesting potential for treating certain male-related health conditions.

The study found that two enzymes linked to hair loss are located in different parts of the scalp, supporting a common treatment's effectiveness.

Dihydrotestosterone treatment can help penis growth in boys with 5α-reductase deficiency but doesn't fully normalize size after puberty.

Testosterone and dihydrotestosterone treatments can help with penile growth in males with 5α-reductase type 2 deficiency, with dihydrotestosterone being more effective in infancy.

Finasteride helps treat hair loss and prostate enlargement by blocking a specific enzyme.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

5α-reductase inhibitors, like finasteride and dutasteride, effectively treat BPH, male baldness, and hirsutism, with potential for acne and prostate cancer prevention.

Young girls whose mothers have PCOS may have higher activity of a specific enzyme that could lead to developing PCOS later.

Saw palmetto extract can block the enzyme that converts testosterone in pig prostate cells.

Inhibiting 5α-reductase can help reduce prostate cancer risk and improve treatment.

Blocking the enzyme 5α-reductase can shrink the prostate and help treat enlarged prostate issues.