Longitudinal Clinical Course in Patients With 5α-Reductase Type 2 Deficiency Treated With Testosterone and Dihydrotestosterone During Infancy and Puberty

    October 2022 in “ Endocrine journal ”
    Daisuke Ariyasu, Fusa Nagamatsu, Keiko Aso … Yukihiro Hasegawa
    Studysummary In this study of male patients with 46,XY 5α-reductase type 2 deficiency, DHT therapy was effective in achieving penile enlargement during infancy, while testosterone replacement therapy proved more beneficial during puberty, possibly due to increased conversion to DHT.
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    Research cited in this study 1

    1. Effects of Pre- and Post-Pubertal Dihydrotestosterone Treatment on Penile Length in 5α-Reductase Type 2 Deficiency Endocrine journal · 2019

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    1. Testosterone Therapy for Osteoporosis in Men Elsevier eBooks · 2010