35 citations
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January 2018 in “Vitamins and hormones” This review examines the physiological, biochemical, and molecular mechanisms by which DHEA and DHEA-S influence various bodily systems, citing rodent studies, but presents no new clinical results.
33 citations
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August 2000 in “Experimental Cell Research” 22 citations
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November 2024 in “Bioactive Materials” This study found that 3D-printed polyamine-modified hydrogels facilitate M2 macrophage polarization and exosome secretion, enhancing skin cell compatibility and promoting wound healing and hair follicle induction in an animal model through specific signaling pathways, suggesting potential for skin disorder therapies.
17 citations
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September 2024 in “Journal of Ginseng Research” This review discusses recent in vitro and in vivo research suggesting that components of ginseng, such as ginsenosides and gintonin, may have potential skincare benefits, including anti-aging effects and treatment of skin conditions like atopic dermatitis and hypertrophic scars.
17 citations
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April 2006 in “Brain Research” This study found that stimulation with certain neurotransmitters and hormones suggests the involvement of 5α-reduced neurosteroids in glial cell differentiation in rat C6 glioma cells.
11 citations
,
July 2004 in “Journal of Investigative Dermatology” Certain tyrosine kinases may regulate hair growth and could help develop hair loss treatments.
9 citations
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November 2024 in “Journal of Wound Management Official journal of the European Wound Management Association” Cold Plasma shows promise for healing wounds by killing bacteria and helping tissue grow.
9 citations
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April 2019 in “Bioscience, biotechnology, and biochemistry” This research identified key miRNAs involved in sheep fetal hair follicle development, highlighting the prolactin signaling pathway and platelet activation as critical processes in secondary follicle initiation.
8 citations
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July 2024 in “Journal of Advanced Research” In this study, researchers report that CDK inhibitors like palbociclib and ribociclib, initially developed for cancer therapy, show potential in treating neutrophilic inflammation-related conditions such as ARDS and psoriasis, although their clinical repurposing requires further research on safety and dose adjustments.
7 citations
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January 2020 in “The journal of investigative dermatology/Journal of investigative dermatology” This study shows that NIPP1 deficiency in mouse epidermis leads to hyperproliferation, hair loss, and chronic skin inflammation, which can be partially alleviated by dexamethasone treatment.
6 citations
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December 2024 in “F1000Research” In this review, the researchers highlight the role of fibroblasts in regulating the extracellular matrix and immune responses, emphasizing the impact on macrophages and potential therapeutic insights for fibrotic diseases and cancer.
5 citations
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December 2023 in “Current Biology” A feedback loop between LRH and RSL4 controls root hair growth in Arabidopsis.
2 citations
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August 2006 in “Journal of Dermatological Science” Automated image analysis helps diagnose and monitor alopecia areata by efficiently measuring hair follicles.
May 2025 in “Cellular Oncology” This study suggests that dual inhibition of P-cadherin and c-Met could be an effective treatment strategy for head and neck squamous cell carcinoma by targeting resistant tumor cells.
3 citations
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June 2022 in “Dermatology and therapy” This case report found that a novel botanical treatment halted disease progression and promoted hair regrowth in four patients with lichen planopilaris, indicating potential for use as a safe alternative therapy.
301 citations
,
May 1998 in “Genes & Development” Ets2 gene is crucial for placental development in mice.
76 citations
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July 2019 in “Cellular and Molecular Life Sciences” This article reviews the role of stem cells in tissue development, tumor formation, and organoid generation, and highlights the potential of epigenetic regulation in advancing regenerative medicine and cancer treatment, without presenting new experimental results.
15 citations
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August 2022 in “Journal of endocrinological investigation” This review discusses how vitamin D and calcium signaling are essential for wound healing by activating epidermal and hair follicle stem cells, noting that deficiencies may lead to delayed or chronic wounds.
3 citations
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April 2021 in “Journal of Medicinal Chemistry” This study suggests that finasteride may inhibit the enzyme PNMT, potentially contributing to its sexual and psychological side effects.
2 citations
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February 2025 in “Applied Microbiology and Biotechnology” This study suggests that Isaria cicadae Miquel rice fermentation extract may enhance regenerative wound healing of hair follicles in mouse skin through the Hippo pathway mechanism.
5 citations
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November 2024 in “Naunyn-Schmiedeberg s Archives of Pharmacology” This review highlighted the role of microRNAs (miRNAs) in gouty arthritis, emphasizing their potential influence on disease progression through immune and inflammatory regulation, and their prospective use in diagnosis, prognosis, and therapy.
September 1984 in “Journal of Biological Education” Human hair growth involves active, resting, and intermediate phases, and examining plucked hairs can teach students about hair biology and diseases.
9 citations
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March 2019 in “Scientific reports” This study found that transient non-lethal levels of endogenous ROS in cultured human hair follicles promoted entry into the growth phase by activating the hair follicle stem cell niche.
1 citations
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September 1984 in “Journal of Biological Education” Plants change their growth in response to shade based on light signals detected by phytochrome.
December 2023 in “Journal of the Endocrine Society” In this study, the researchers found that glucocorticoid receptor activation may influence glucose metabolism, with preventive GR antagonist treatment reducing hyperglycemia and restoring glucose tolerance in a PCOS mouse model.
In this study, a Monte Carlo-generated synthetic cohort analysis found that higher simulated cannabis exposure was linked to increased self-assessed hair loss severity and reduced follicular density, suggesting potential connections worth exploring in further clinical research.
1 citations
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March 2024 in “Signal transduction and targeted therapy” In this review, researchers explored the multifaceted role of NF-κB signaling in various biological processes and diseases, including its interactions with other pathways, and discussed possible therapeutic approaches targeting this pathway for treating conditions like cancer, autoimmune disorders, and COVID-19.
1 citations
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January 2019 in “The International Journal of Lower Extremity Wounds” This study demonstrated in rodent models that artificial dermal template treatment can induce full-thickness skin regrowth including skin epidermis and adnexa without the need for autologous skin grafts.
7 citations
,
June 2021 in “Amino acids” This study found that protein arginine methylation levels in human hair may correlate with a cardiovascular biomarker in blood, suggesting hair sampling as a potential non-invasive method for cardiovascular risk assessment.
1 citations
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May 2026 in “Nature Communications” This study demonstrated that CD19-CAR T cell therapy may promote structural regeneration in the skin of systemic sclerosis patients, as evidenced by histological improvements and fibroblast population changes, suggesting its potential for tissue remodeling in fibrotic diseases.