Modeling Oxidative Stress-Linked Telogen Effluvium Using Monte Carlo Simulation of Published Trichoscopy Norms and Cannabis Exposure Distributions

    January 2026 in “ Cureus ”
    Aryan Chadha, Qiang Wang, Samuel Poelker-Wells
    Studysummary In this study, a Monte Carlo-generated synthetic cohort analysis found that higher simulated cannabis exposure was linked to increased self-assessed hair loss severity and reduced follicular density, suggesting potential connections worth exploring in further clinical research.
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    Research cited in this study 10

    1. Oxidative Stress in Hair Follicle Development and Hair Growth: Signaling Pathways, Intervening Mechanisms and Potential of Natural Antioxidants Journal of Cellular and Molecular Medicine · 2024
    2. Quantitative Measurement of Hair Diameter Diversity as a Diagnostic Indicator of Androgenetic Alopecia in Korean Males: A Cross-Sectional Study JAAD International · 2024
    3. Trichoscopy Patterns in Alopecia Areata: A Systematic Review and Meta-Analysis Skin Research and Technology · 2023
    4. A Clinico-Trichoscopic Analysis of Hair Density and Diameter Variability in Relation to Severity Grading of Female Pattern Hair Loss International Journal of Trichology · 2022
    5. Cannabinoid Signaling in the Skin: Therapeutic Potential of the Cutaneous Cannabinoid System Molecules/Molecules online/Molecules annual · 2019
    6. Telogen Effluvium: A Review Journal of Clinical and Diagnostic Research · 2015
    7. Diffuse Hair Loss: Its Triggers and Management Cleveland Clinic Journal of Medicine · 2009
    8. Oxidative Stress in Aging of Hair International Journal of Trichology · 2009
    9. Chronic Telogen Effluvium: A Study of 5 Patients Over 7 Years Journal of The American Academy of Dermatology · 2005
    10. Telogen Effluvium: New Concepts and Review Archives of Dermatology · 1993