Thiol/Disulfide Homeostasis in Patients with Telogen Effluvium: Is Oxidative Stress Important in the Pathogenesis of Telogen Effluvium?

The 2019 study investigated the role of oxidative stress in the development of telogen effluvium, a common hair shedding disorder. The study involved 101 patients with telogen effluvium and 39 healthy volunteers. The researchers found significant differences in thiol/disulfide balance, a marker of oxidative stress, between the patient and control groups. This suggests that oxidative stress plays a key role in the development of telogen effluvium. The study concluded that antioxidant treatment could potentially be beneficial for telogen effluvium, but more research is needed to explore the effects of oxidative stress on the disorder using different markers.