Chemoprevention of Doxorubicin-Induced Alopecia in Mice by Dietary Administration of L-Cystine and Vitamin B6

    Francesco D’Agostini, Paolo Fiallo, Massimo Ghio, Silvio De Flora
    Studysummary This study demonstrated that high doses of L-cystine and vitamin B6 effectively prevent doxorubicin-induced hair loss in mice.
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    Research cited in this study 15

    1. Prevention of Chemotherapy-Induced Alopecia in Rodent Models Cell stress & chaperones · 2008
    2. Chemoprevention of Smoke-Induced Alopecia in Mice by Oral Administration of L-Cystine and Vitamin B6 Journal of dermatological science · 2007
    3. Dietary Supplement Increases Anagen Hair Rate in Women With Telogen Effluvium: Results of a Double-Blind, Placebo-Controlled Trial Therapy · 2006
    4. Protection Against Chemotherapy-Induced Alopecia Pharmaceutical Research · 2006
    5. Chemotherapy Targets the Hair Follicle Vascular Network but Not the Stem Cells Journal of Investigative Dermatology · 2006
    6. Hair Follicle-Derived Blood Vessels Vascularize Tumors in Skin and Are Inhibited by Doxorubicin Cancer Research · 2005
    7. Nascent Blood Vessels in the Skin Arise from Nestin-Expressing Hair-Follicle Cells Proceedings of the National Academy of Sciences · 2004
    8. Nestin Expression in Hair Follicle Sheath Progenitor Cells Proceedings of the National Academy of Sciences · 2003
    9. Cutaneous Metabolism of Vitamin B-6 ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2003
    10. Optimal Management of Hair Loss (Alopecia) in Children American Journal of Clinical Dermatology · 2003
    11. Defolliculated (Dfl): A Dominant Mouse Mutation Leading to Poor Sebaceous Gland Differentiation and Total Elimination of Pelage Follicles Journal of Investigative Dermatology · 2002
    12. Prevention of Chemotherapy-Induced Alopecia in Rats by CDK Inhibitors Science · 2001
    13. Idiopathic Chronic Telogen Effluvium in Women Der Hautarzt · 2000
    14. Metabolism of Freshly Isolated Human Hair Follicles Capable of Hair Elongation: A Glutaminolytic, Aerobic Glycolytic Tissue Journal of Investigative Dermatology · 1993
    15. Studies on the Effect of Thallium Poisoning of the Rat ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 1948

    Related research 4

    1. Role of Low Dose Oral Minoxidil in the Treatment of Hair Loss: A Review Cosmoderma · 2021
    2. A Case Report of Chemotherapy-Induced Alopecia Treated with Bojungikki-Tang The Journal of Internal Korean Medicine · 2017
    3. Chemoprevention of Doxorubicin-Induced Alopecia in Mice by Dietary Administration of L-Cystine and Vitamin B6 Archives of Dermatological Research · 2012
    4. Minoxidil as a Prophylaxis of Doxorubicin-Induced Alopecia Annals of Oncology · 1994