Modeling Oxidative Stress-Linked Telogen Effluvium: A Monte Carlo Simulation Using Published Trichoscopy Norms and Cannabis Exposure Distributions

    December 2025
    Aryan Chadha, Margit Burmeister, Samuel Poelker-Wells … Samuel Poelker-Wells
    Studysummary This simulation study found that higher cannabis exposure in a virtual population was associated with increased hair shedding severity and reduced follicular density, but these results are based on modeled data and cannot establish causal relationships.
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    Research cited in this study 9

    1. Oxidative Stress in Hair Follicle Development and Hair Growth: Signaling Pathways, Intervening Mechanisms and Potential of Natural Antioxidants Journal of Cellular and Molecular Medicine · 2024
    2. The Biology and Genomics of Human Hair Follicles: A Focus on Androgenetic Alopecia International Journal of Molecular Sciences · 2024
    3. Oxidative Stress-Associated Senescence in Dermal Papilla Cells of Men with Androgenetic Alopecia Journal of Investigative Dermatology · 2015
    4. Telogen Effluvium: A Review Journal of Clinical and Diagnostic Research · 2015
    5. Diffuse Hair Loss: Its Triggers and Management Cleveland Clinic Journal of Medicine · 2009
    6. Oxidative Stress in Aging of Hair International Journal of Trichology · 2009
    7. Hormonal Regulation of Hair Follicles Exhibits a Biological Paradox Seminars in Cell & Developmental Biology · 2007
    8. Chronic Telogen Effluvium: Increased Scalp Hair Shedding in Middle-Aged Women Journal of The American Academy of Dermatology · 1996
    9. Telogen Effluvium: A Comprehensive Review Archives of Dermatology · 1993