Intrinsic Activation of Cell Growth and Differentiation in Ex Vivo Cultured Human Hair Follicles by a Transient Endogenous Production of ROS

    March 2019 in “ Scientific reports ”
    María I. Calvo-Sánchez, Sandra Fernández-Martos, Juan José Montoya, Jesús Espada
    Studysummary This study found that transient non-lethal levels of endogenous ROS in cultured human hair follicles promoted entry into the growth phase by activating the hair follicle stem cell niche.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on nature.com →
    Discuss this study in the Community →

    Research cited in this study 5

    1. Emerging Interactions Between Skin Stem Cells and Their Niches Nature Medicine · 2014
    2. In Vivo Transcriptional Governance of Hair Follicle Stem Cells by Canonical Wnt Regulators Nature Cell Biology · 2014
    3. Mitochondrial Reactive Oxygen Species Promote Epidermal Differentiation and Hair Follicle Development Science Signaling · 2013
    4. VEGF Induces Proliferation of Human Hair Follicle Dermal Papilla Cells Through VEGFR-2-Mediated Activation of ERK Experimental Cell Research · 2012
    5. Control of Hair Growth and Follicle Size by VEGF-Mediated Angiogenesis Journal of Clinical Investigation · 2001