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Glossary Hair Growth-Related Genes

specific genes that regulate hair follicle development and cycling

Hair Growth-Related Genes are specific genes that play a crucial role in regulating the development, cycling, and maintenance of hair follicles. These genes influence various biological processes such as cell proliferation, differentiation, and signaling pathways that are essential for hair growth. Mutations or variations in these genes can lead to conditions like alopecia or other hair growth disorders.

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Research

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Medications Affecting the Insulin-Like Growth Factor 1/Growth Hormone Axis, Including Teprotumumab, Somatostatin Analogs, and Anti-Calcitonin Gene-Related Peptide Monoclonal Antibodies, Are Associated With Elevated Reporting Odds of Alopecia in Women: A Pharmacovigilance Study

research Medications affecting the insulin-like growth factor 1/growth hormone axis, including teprotumumab, somatostatin analogs, and anti-calcitonin gene-related peptide monoclonal antibodies, are associated with elevated reporting odds of alopecia in women: A pharmacovigilance study

April 2023 in “Journal of The American Academy of Dermatology”

This study investigated the association between hair loss and medications affecting the GH/IGF-1 pathway, using the FDA Adverse Event Reporting System to analyze reporting odds ratios of alopecia.

research Investigation of the differential effect of juice or water extract from Puerariae Radix on hair growth related-genes in dermal papilla cells

January 2018 in “The Korea Journal of Herbology”

This study found that water extract of Puerariae Radix may promote hair growth by increasing the mRNA expression levels of hair growth-related genes in human dermal papilla cells, unlike the juice extract.

research Change in Hair Growth-related Gene Expression Profile in Human Isolated Hair Follicles Induced by 5-alpha Reductase Inhibitors, Dutasteride and Finasteride, in the Presence of Testosterone

January 2019

This study suggests that 5AR inhibitors may reverse decreased expression of growth factor genes in human hair follicles under testosterone stimulation, indicating involvement of type I 5AR in hair growth.

Recent Advances in Neuropeptide-Related Omics and Gene Editing: Spotlight on NPY and Somatostatin and Their Roles in Growth and Food Intake of Fish

research Recent advances in neuropeptide-related omics and gene editing: Spotlight on NPY and somatostatin and their roles in growth and food intake of fish

October 2022 in “Frontiers in Endocrinology”

This review discusses recent advancements in omics and gene editing technologies for studying neuropeptides and receptors in fish, but reports no new experimental findings; the authors highlight the need for further research in this area.

research Expression of the Scube3 epidermal growth factor-related gene during early embryonic development in the mouse

17 citations , December 2006 in “Gene Expression Patterns”

This study reports that the mouse Scube3 gene is expressed in various tissues during embryonic development, including the neural tube, limb buds, developing tooth, hair follicle, and skeletal regions.

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Community Join

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community Bloodflow? Does it affect hair growth?

23 upvotes 7 years ago

Hair loss is primarily caused by genetic sensitivity to DHT, not lifestyle factors like diet or exercise. Treatments like Minoxidil and Finasteride can help, but it's important to consult a dermatologist to determine the best approach for individual cases.

community Intermittent fasting reduces hair growth?!? :(

35 upvotes 1 year ago

Intermittent fasting may inhibit hair growth by triggering a stress response that affects hair-follicle stem cells. Some users believe genetics and DHT play a larger role in hair loss, and treatments like Minoxidil and Finasteride are mentioned as ineffective for some.

community How many of you guys have taken accutane?

in Chat 8 upvotes 1 year ago

Accutane may accelerate hair loss in genetically predisposed individuals by affecting enzymes related to DHT metabolism. Some users report hair loss after taking Accutane, while others use treatments like finasteride and minoxidil to manage hair loss.

community Keratin microspheres - breakthrough

14 upvotes 2 years ago

A gel of keratin microspheres promotes hair follicle growth, showing similar effectiveness to minoxidil in mice. The treatment activates hair growth pathways and reduces inflammation, with potential applications in drug delivery for hair-related disorders.

community Considering Quitting Topical Min

1 year ago

The user is considering stopping topical minoxidil due to lack of improvement in hair growth and is exploring alternatives like oral minoxidil, topical finasteride, and tretinoin. They are hesitant about oral finasteride and dutasteride, and are open to trying oral minoxidil if available, despite concerns about potential heart-related side effects.

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Learn

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learn Epidermal Growth Factor

learn Vitamin D

vitamin you should probably be taking for general health might also help your hair a little

learn sh-Polypeptide-7

learn Fluridil

a topical anti-androgen with less systemic involvement

learn Cyproterone

a synthetic anti-androgen and weak progestogen that inhibits DHT binding to androgen receptor

learn Follistatin

What is follistatin, and how does it influence hair follicle growth and regeneration? Follistatin blocks activin and related growth-inhibiting proteins, which in laboratory and animal work is described as keeping hair follicles in their growth phase; the only verifiable human evidence is a single small 2011 phase 1 injection trial, so follistatin remains experimental and is not an approved hair-loss treatment.

learn Pyrithione Zinc

How does pyrithione zinc help reduce dandruff and irritation related to hair loss? Pyrithione zinc reduces dandruff and irritation by inhibiting yeast growth on the scalp.

learn Centella

Got small bald circles with no warning? Centella creams might calm the area and kickstart new growth. There is no published human trial of Centella asiatica for alopecia areata or any other hair loss; the only hair-related studies are cell-culture work. Community users describe Centella creams as soothing for an irritated scalp, not as regrowth treatments, and a new bald patch needs a doctor's diagnosis first.

learn Hair Transplant

What are the risks and side effects of FUE hair transplants? Providers describe most FUE side effects, such as swelling, redness, numbness and shock loss, as temporary, but FUE is surgery and the same sources report pain, infection, folliculitis and small permanent donor-site scars. Longer-lasting problems, including visible donor-area thinning or poor graft growth, are possible and are not covered by this provider survey.

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Clinics

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Experts

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22
Hair System Specialist
Jane Genesi
Marlton, PA, United States

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Jane Genesi