Cold Plasma: An Emerging Technology for Clinical Use in Wound Healing
TLDR Cold Plasma shows promise for healing wounds by killing bacteria and helping tissue grow.
Cold Atmospheric Plasma (CAP) is emerging as a promising technology for wound healing due to its antimicrobial efficacy and ability to stimulate tissue regeneration. CAP generates reactive oxygen and nitrogen species (RONS), which are crucial for cellular signaling and wound healing. Studies have shown CAP's effectiveness in reducing bacterial load, enhancing micro-circulation, and accelerating wound closure in both preclinical and clinical settings. CAP has demonstrated safety and efficacy in various animal models and human trials, particularly for chronic wounds. However, the treatment's efficacy depends on the dose and application method, and further research is needed to optimize treatment protocols and understand its molecular mechanisms. Despite challenges in regulatory classification and standardization, CAP offers a non-invasive alternative to conventional therapies and shows potential in other medical applications, including cancer treatment and sterilization.