1 citations
,
April 2018 in “Lasers in Surgery and Medicine” This review summarizes late-breaking abstracts from the American Society for Laser Medicine and Surgery, 2018, and reports no new clinical findings.
1 citations
,
May 2017 in “InTech eBooks” This review discusses various treatments for noncicatricial alopecias, such as androgenetic alopecia and alopecia areata, including mesotherapy, microneedling, and platelet-rich plasma therapy, noting that outcomes vary across these procedures.
87 citations
,
August 2017 in “Scientific Reports” This study found that PCL-based nanofiber scaffolds enhanced cell proliferation and extracellular matrix deposition, suggesting they show promise as a cell delivery system for improving skin wound healing.
2 citations
,
April 2025 in “Cells” This study found that heat preconditioning of nanofat from mice did not improve tissue vascularization or integration in grafting, and actually reduced vascularization due to increased expression of anti-angiogenic factors, suggesting it is not beneficial for enhancing its vascularization properties.
May 2025 in “Journal of International Medical Research” In this study, micrografting technology was found to potentially shorten healing time compared to other grafting techniques, especially in treating burns, though results showed high heterogeneity and a risk of bias.
January 2023 in “Medicines” This study reported that using micronized-gingival connective tissues appeared safe and showed initial efficacy for reconstructing peri-implant soft tissues, suggesting potential as an alternative to traditional grafting methods.
This systematic review reports positive outcomes for platelet-rich plasma in aesthetic dermatology applications like skin rejuvenation, hair restoration, wound healing, and fat grafting, but highlights the need for standardized protocols in future research.
1 citations
,
October 1996 in “Dermatologic clinics” This study found that higher levels of adiponectin were associated with reduced inflammation and osteolysis, suggesting potential therapeutic benefits for patients with aseptic loosening of joint replacements.
3 citations
,
November 2015 in “Jurnal Online Universitas Gadjah Mada (Universitas Gadjah Mada)” In this study, multiple mini punch grafts significantly improved epithelialization, covering more than 90% of a large ulcer in a 6-year-old boy after eight weeks.
35 citations
,
October 2014 in “Wound Repair and Regeneration” This study developed a validated murine model of hypertrophic scar contraction, demonstrating similarities to human skin and observing graft contraction and tissue characteristics over time.
4 citations
,
August 2024 in “Health Science Reports” This study found that using hair follicle units to treat hard-to-heal wounds led to complete or partial closure in most patients, with reduced operation time, minimal morbidity, and low complication rates and costs.
5 citations
,
March 2016 in “Experimental and molecular pathology” In mouse models of alopecia areata, this study found increased dilation of lymphatic vessels in affected mice, with associated changes in gene expression related to vascular growth and immune cell movement.
14 citations
,
May 2011 in “Physical medicine and rehabilitation clinics of North America” This article discusses the growing focus on long-term outcomes in burn care, emphasizing the importance of coordinated team approaches in burn reconstruction, but it presents no new clinical findings.
41 citations
,
January 2015 in “Burns & Trauma” This review discusses developments in tissue engineering for burn wound coverage and reconstructive surgery, reporting no new results but highlighting the need for further research into clinical effectiveness.
28 citations
,
November 2020 in “Polymers” This study found that crosslinking buffalo gelatin with different methods can modify its properties and potential as a skin substitute, though double-crosslinking may increase immunogenicity slightly.
September 2024 in “Journal of Cutaneous and Aesthetic Surgery” This case report detailed a successful treatment involving contracture release and expanded neck flap reconstruction for a patient with severe neck contracture and beard alopecia from past thermal burns, highlighting improved skin quality and hair regrowth following follicular unit extraction.
This study suggests that a portable OCT system may be useful for the clinical diagnosis and evaluation of skin diseases and laser treatment outcomes.
This review examines the potential of stem cells and their derived products, such as exosomes and conditioned media, in improving burn wound healing but presents no new clinical data.
April 2026 in “Clinical Cosmetic and Investigational Dermatology” This review highlights the varied therapeutic applications of punch-based techniques in dermatologic surgery, noting consistent evidence for follicular unit extraction in androgenetic alopecia, but more mixed results for scar treatment, vitiligo, and chronic wounds, warranting further standardized research.
The systematic review reported promising outcomes for stem cell-enriched treatments in aesthetic medicine, such as improved skin rejuvenation, hair restoration, and scar revision. However, challenges like protocol variability and regulatory issues must be addressed to ensure effective and safe clinical applications.
92 citations
,
April 1999 in “The journal of investigative dermatology/Journal of investigative dermatology” This study suggests that keratin 9 expression in nonpalmoplantar keratinocytes can be induced by signals from palmoplantar fibroblasts, potentially enabling the use of nonpalmoplantar epidermis to treat palmoplantar wounds.
2 citations
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July 2025 in “Journal of Plastic Reconstructive & Aesthetic Surgery” This review discusses the role of hair follicles in wound healing and scar remodeling, emphasizing that hair follicle transplantation may aid in faster wound closure and scar reduction by enhancing the cellular and molecular mechanisms involved in scarring.
September 2023 in “International Journal of Trichology” In this study reviewing recent literature, researchers found limited high-quality evidence supporting the use of adipose-derived stem cells for androgenic alopecia and alopecia areata, suggesting a need for further randomized controlled trials to better assess their efficacy.
July 2024 in “Periodontology 2000” This review summarizes the use of autologous platelet concentrates in aesthetic medicine, finding promising results for facial treatments, but highlights the need for more rigorous research due to current study limitations.
22 citations
,
January 2017 in “Indian Dermatology Online Journal” This review discusses the use of follicular unit extraction for hair restoration using body hair, reporting no new clinical findings, and highlights its potential for advanced baldness cases with limited scalp donor hair.
9 citations
,
July 2024 in “JAAD reviews.” This review discusses the role of extracellular vesicles in dermatology for therapeutic, diagnostic, and prognostic purposes, highlighting the lack of validated findings and the necessity for more rigorous clinical trials.
50 citations
,
May 1999 in “Journal of Reconstructive Microsurgery” This study concluded that microsurgical reconstruction is a reliable method to achieve stable coverage of large, complex scalp defects, although cancer control rates were poor.
1 citations
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August 1988 in “Journal of The American Academy of Dermatology” This study describes a unique case of hair transplantation between monozygotic twins to address congenital, nonprogressive alopecia caused by follicular aplasia in one twin.
This abstract introduces 3D bioprinted skin grafts as a promising alternative to traditional skin grafts, emphasizing how using stem cells in the bioink can enhance vascularization and hair follicle regeneration, potentially improving graft integration and function without the donor site risks.
4 citations
,
December 1992 in “The American Journal of Cosmetic Surgery” The modified S pattern for scalp reduction is effective for removing more bald scalp and hiding scars in hair restoration.