Feature Identification of Skin Diseases and Laser Therapy with a Portable Optical Coherence Imaging System

September 2023

Chien-Yu Lin, Chau Yee Ng, Meng-Tsan Tsai

Optical Coherence Tomography OCT Michelson interferometer picosecond laser treatment laser-induced optical breaks LIOBs epidermis collagen regeneration stratum corneum pore size hair follicle size collagen concentration skin roughness picosecond laser collagen pores hair follicles skin texture

TLDR A portable imaging system shows promise for diagnosing skin diseases and checking laser treatment effects.

The document discusses a study that utilized a portable Optical Coherence Tomography (OCT) system and a handheld probe for in vivo scanning of arbitrary skin locations. The OCT system, based on a fiber-based Michelson interferometer, can provide non-invasive, high-speed, label-free, and 3D imaging of skin structures without the need for contrast agents or dyes. The system was used to evaluate the effects of picosecond laser treatment on human skin. The results showed that the OCT system could identify morphological changes due to diseases and treatment, including the detection of laser-induced optical breaks (LIOBs) in the epidermis layer, which can induce collagen regeneration after recovery. The system can also simultaneously acquire skin parameters such as thickness of stratum corneum, thickness of epidermis, pore/hair follicle size, collagen concentration, and skin roughness.

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