Systematic Review and Meta-Analysis of the Use of Micrografting Technology in Humans

The systematic review and meta-analysis assessed the effectiveness of micrografting technology, particularly the Rigenera system, across various medical conditions, including burns, wounds, ulcers, vitiligo, and androgenetic alopecia. It included 55 studies, with 7 focusing on androgenetic alopecia. One study with 100 participants showed an increase in hair density from 15 to 48.5 hairs/cm² after 2 months of treatment. The review found that micrografting may lead to shorter healing times and improved outcomes, but the evidence was inconsistent with a moderate risk of bias and high heterogeneity. Further research is needed to standardize protocols and establish clinical guidelines, although micrografting shows potential benefits, especially when traditional treatments are inadequate.