A Retrospective Study on the Use of Dermis Micrografts in Platelet-Rich Fibrin for the Resurfacing of Massive and Chronic Full-Thickness Burns
September 2019
in “
Stem Cells International
”
Studysummary This study observed that a treatment combining platelet-rich fibrin and micrograft spray-on skin led to rapid and complete wound healing in both massive and chronic burn patients within an average of 7-10 days. Our plain-language summary of this paper — not a Tressless recommendation.
This retrospective study investigated the use of autologous micrografts combined with platelet-rich fibrin (PRF) for treating massive and chronic full-thickness burns in five male patients. The technique involved applying a solution of micrografts and PRF to the wound bed, followed by meshed skin grafting. The study found high graft take rates (96%-98%) and successful wound healing, with complete reepithelialization occurring within days. The approach showed potential as an effective treatment, particularly in resource-limited settings, although the small sample size and retrospective design indicated the need for further randomized trials to confirm efficacy.
