A Retrospective Study on the Use of Dermis Micrografts in Platelet-Rich Fibrin for the Resurfacing of Massive and Chronic Full-Thickness Burns

    September 2019 in “ Stem Cells International ”
    Alessandro Andreone, Daan den Hollander
    TLDR The PRF/micrograft spray-on skin method effectively healed massive and chronic burns quickly.
    This retrospective study explored the use of a combination of platelet-rich fibrin (PRF) and micrograft spray-on skin for treating massive and chronic full-thickness burns in five patients. The treatment involved using Rigenera technology to create autologous micrografts, which were then combined with PRF and applied to the wound bed using a Spraypen. The wounds were initially prepared with an Integra® dermal template and antimicrobial dressing. The study found that all patients experienced fast and complete skin grafting within 7-10 days. Notably, two patients with massive burns showed rapid reepithelialization, and three patients with chronic burn wounds, including two with previous failed grafts, achieved complete healing within a week. The findings suggested that PRF/micrograft spray-on skin could be a promising method for managing burns and chronic burn wounds.
    Discuss this study in the Community →

    Research cited in this study

    1 / 1 results

    Related Community Posts Join

    6 / 108 results

      community Hairloss after doing PRF treatment

      in Treatment  2 upvotes 2 years ago
      The conversation is about the potential risk of permanent hair loss from PRP (platelet rich plasma) treatments and whether PRF (platelet rich fibrin) carries the same risk. The user is seeking information on this topic.

      community Here is my hair regrowth plan

      in Treatment  4 upvotes 4 years ago
      The user's hair regrowth plan includes topical treatments (RU58841, azelaic acid, ketoconazole), oral supplements (Gia Herbs, castor oil), microneedling, PTD-DBM peptide with valproic acid, red light therapy, inversion table with scalp massage, and platelet-rich fibrin injections. Commenters suggest that finasteride and minoxidil are essential treatments for male pattern hair loss, which are missing from the plan.

      community I have been on finasteride for 9 months. (6 months on 0.25 mg, 3 months into 0.5 mg daily) here are the progress pictures.

      in Progress Pictures  273 upvotes 5 months ago
      A user shared progress pictures after 9 months on finasteride, starting with 0.25 mg and increasing to 0.5 mg daily, noting improved hair density, especially at the crown, with initial side effects that resolved after the first month. The discussion includes user experiences with finasteride, concerns about side effects, and alternative treatments like rosemary oil and platelet-rich plasma therapy.

      community Difference between my hair wet and dry literally an hour apart

      in Finasteride/Dutasteride  757 upvotes 5 months ago
      The conversation is about hair loss treatments, focusing on minoxidil and finasteride, with suggestions for microneedling and dermarolling to improve hair thickness. The original poster has used minoxidil for four years and finasteride for over a year but is exploring additional options for better results.

    Similar Research

    5 / 1000+ results