Impact of Stem Cell-Based Therapy and Platelet-Rich Plasma in Hair Loss and Telogen Effluvium Related to COVID-19

December 2023 in “ Regenerative Therapy ”

Pietro Gentile, Simone Garcovich

hair loss telogen effluvium COVID-19 Platelet-Rich Plasma Adipose-derived Mesenchymal Stem Cells Human Follicle Stem Cells regenerative strategies stem cell-based therapies HL TE PRP AD-MSCs HFSCs

TLDR Stem cell and platelet-rich plasma therapies show promise for COVID-19 related hair loss, but more research is needed.

The systematic review analyzed 12 studies to evaluate the increased incidence of hair loss (HL) and telogen effluvium (TE) in COVID-19 patients, and the effectiveness of Platelet-Rich Plasma (PRP), Adipose-derived Mesenchymal Stem Cells (AD-MSCs), and Human Follicle Stem Cells (HFSCs) in these patients. The data confirmed an increased incidence of HL and TE in COVID-19 patients and the preliminary effectiveness of AD-MSCs, HFSCs, and PRP without major side effects. 84% of the studies showed a clear correlation between HL, TE, and COVID-19, and 68% of the studies showed a positive impact of regenerative strategies, including PRP and stem cell-based therapies, against HL related to COVID-19. However, the review highlighted the need for further research to define standardized protocols and large-scale trials to confirm the effectiveness of these regenerative therapies.

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