Platelet-Rich Plasma in Aesthetic Dermatology: Current Evidence and Future Directions

Platelet-rich plasma (PRP) shows promise in aesthetic dermatology, particularly for skin rejuvenation, hair restoration, wound healing, and fat grafting. A systematic review of 13 studies found significant improvements in collagen density, skin appearance, hair density (18-27.7 hairs/cm²), wound healing, and fat graft survival. Patient satisfaction was high, and PRP demonstrated a favorable safety profile. However, there was notable variability in PRP preparation and treatment protocols, indicating a need for standardized methods. Future research should focus on large-scale randomized controlled trials with standardized protocols and longer follow-up periods to strengthen the evidence base for PRP applications.