Current Evidence for Clinical Efficacy of Platelet-Rich Plasma in Aesthetic Surgery: A Systematic Review

November 2016 in “ Aesthetic surgery journal ”

Russell S. Frautschi, Ahmed M. Hashem, Brianna Halasa, Çağrı Çakmakoğlu, James E. Zins

platelet-rich plasma PRP scalp alopecia aging skin lipofilling fractional laser facial surgery

TLDR The document concludes that the effectiveness of platelet rich plasma in aesthetic surgery is unclear due to inconsistent reporting and lack of objective measures in studies.

The document reviewed the use of platelet rich plasma (PRP) in aesthetic surgery and found that while PRP is claimed to be effective in 95% of the studies, objective measures were only used in 47% of them. The review included 38 reports with applications in aging skin (29%), scalp alopecia (26%), lipofilling (21%), fractional laser (13%), and facial surgery (11%). The majority of studies were case series without controls, and there was a lack of consistent reporting on PRP preparation, composition, and activation. Only 18% of studies clarified platelet concentration, and the activation mechanism was described in 71% of studies, while anticoagulation was detailed in 47%. Due to the context-dependent results and inconsistent reporting, meaningful meta-analysis was deemed unrealistic, and the authors recommended a set of descriptors, FIT PAAW, to standardize reporting and better understand PRP's effectiveness.

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research The Effect of Platelet-Rich Plasma in Hair Regrowth: A Randomized Placebo-Controlled Trial

214 citations , September 2015 in “Stem Cells Translational Medicine”

Platelet-rich plasma injections significantly improved hair regrowth and thickness in patients with hair loss.

research Platelet-Rich Plasma as a Potential Treatment for Noncicatricial Alopecias

58 citations , January 2015 in “International Journal of Trichology”

Platelet-rich plasma, which carries growth factors, could be a promising treatment for non-scarring hair loss, promoting hair growth and density with no major side effects.

research Role of Platelet-Rich Plasma in Chronic Alopecia Areata: Our Centre Experience

61 citations , January 2015 in “Indian Journal of Plastic Surgery”

Platelet-rich plasma treatment could potentially be an effective way to treat chronic alopecia areata with minimal side effects.

research Therapeutic Efficacy of Autologous Platelet-Rich Plasma and Polydeoxyribonucleotide on Female Pattern Hair Loss

54 citations , January 2015 in “Wound Repair and Regeneration”

PRP injections may improve hair thickness and density in female hair loss patients.

research Platelet-Rich Plasma for Androgenetic Alopecia

107 citations , September 2014 in “Dermatologic Surgery”

PRP injections improve hair thickness for baldness.

research The Effect of CD34+ Cell-Containing Autologous Platelet-Rich Plasma Injection on Pattern Hair Loss: A Preliminary Study

88 citations , January 2014 in “Journal of The European Academy of Dermatology and Venereology”

Injecting CD34+ cell-containing platelet-rich plasma into the scalp can improve hair count and thickness in people with pattern hair loss.

research The Effect of Autologous Activated Platelet Rich Plasma Injection on Pattern Hair Loss: Clinical and Histomorphometric Evaluation

183 citations , January 2014 in “BioMed Research International”

AA-PRP injections effectively increase hair count and thickness for male pattern hair loss.

research Platelet-Rich Plasma in Dermatology: Boon or Bane?

119 citations , January 2014 in “Indian Journal of Dermatology, Venereology and Leprology”

Platelet-rich plasma might help with hair growth and skin conditions, but more research is needed to prove its effectiveness and safety.

research Platelet-Rich Plasma in Androgenic Alopecia: Myth or Effective Tool

115 citations , January 2014 in “Journal of Cutaneous and Aesthetic Surgery”

Platelet-rich plasma (PRP) is a cheap and easy treatment for hair loss, but not suitable for everyone. It also helps in healing ulcers, rejuvenating skin, and improving hair transplants.

research A Randomized, Double-Blind, Placebo- and Active-Controlled, Half-Head Study to Evaluate the Effects of Platelet-Rich Plasma on Alopecia Areata

205 citations , August 2013 in “British Journal of Dermatology”

Platelet-rich plasma treatment significantly increased hair regrowth and decreased discomfort in alopecia patients, making it a potentially better and safer treatment option.

research Enhanced Effect of Platelet-Rich Plasma Containing a New Carrier on Hair Growth

166 citations , December 2011 in “Dermatologic Surgery”

Platelet-rich plasma with a new carrier significantly increases hair thickness without serious side effects.

research The Role of Platelet Plasma Growth Factors in Male Pattern Baldness Surgery

251 citations , November 2006 in “Plastic and reconstructive surgery/PSEF CD journals”

Using platelet plasma growth factors in baldness surgery can increase the number of hair follicles.

1 / 1 results

research Comparison of the Efficacy of Homologous and Autologous Platelet-Rich Plasma for Treating Androgenic Alopecia

24 citations , February 2018 in “Aesthetic Plastic Surgery”

All types of Platelet-Rich Plasma (PRP) can treat hair loss, but homologous PRP works best due to its higher platelet count and growth factors from multiple donors.