This study discusses the safety, complications, and limitations of melanocyte transplantation for treating vitiligo, noting that these techniques are generally safe and often combined with medical treatments for repigmenting stable vitiligo macules.
39 citations
,
September 2011 in “Tissue Engineering Part B-reviews” This report reviews current advances in hair follicle regeneration for tissue-engineered skin grafts and highlights the feasibility and challenges of creating human hair follicles in this setting, suggesting key bioengineering requirements.
20 citations
,
April 2011 in “Dermatologic Surgery” Laser therapy helped new hair grow in scarred skin for three patients.
5 citations
,
March 2017 in “Cell and Tissue Banking” In this study, noncultured autologous skin cells prepared using a tissue homogenizer significantly improved burn wound healing in rats compared to a control treatment.
January 2026 in “Indian Journal of Plastic Surgery” This study evaluated nonculture epidermal suspension for stable vitiligo and found it to be effective, with 68% mean repigmentation and 43.1% of patients achieving excellent results; it showed sustained benefits over long-term follow-up and was generally safe with minor adverse events in 13.7% of participants.
40 citations
,
January 2009 in “Skin Pharmacology and Physiology” This review discusses the potential use of cultured primary fetal cells from a single organ donation to produce therapeutic products, emphasizing the need for process consistency and safety verification, but reports no clinical results.
9 citations
,
September 1997 in “Dermatologic Surgery” In this paper, the authors describe a standardized micrografting technique for hair transplantation that significantly speeds up the procedure and minimizes surgical trauma, enhancing graft survival.
26 citations
,
October 2012 in “Dermatologic Clinics” This article reviews recent advancements in hair transplantation techniques, particularly follicular unit transplantation, and suggests an expansion of its applications beyond male pattern hair loss, but reports no new results.
262 citations
,
May 2017 in “Nanomedicine” This review examines recent advancements in electrospun nanofibers for wound healing applications, but reports no new experimental results, highlighting their potential in sutures, dressings, and skin regeneration.
28 citations
,
July 2013 in “Journal of Craniofacial Surgery” In this study, hair follicle transplantation on scars showed varied success rates, with burn scars achieving better results than incision scars, and often requiring multiple procedures for optimal outcomes.
26 citations
,
July 2006 in “Current Opinion in Otolaryngology & Head and Neck Surgery” This review discusses advancements in techniques for scalp reconstruction, highlighting improved cosmetic outcomes and reduced morbidity, but reports no new clinical results.
20 citations
,
February 1991 in “The Journal of Dermatologic Surgery and Oncology” This article discusses scalp reconstruction techniques using rotation flaps, with no new clinical results reported.
19 citations
,
March 2017 in “PLoS ONE” This study found that intact pilosebaceous units were more effective than truncated hair follicles at regenerating a multilayered epidermis in a de-epidermalized dermis in vitro.
6 citations
,
June 2016 in “Journal of Craniofacial Surgery” This study reports that using a combined approach of free osteoseptocutaneous fibula flap and temporal artery-based scalp flap provided satisfactory aesthetic and functional outcomes in reconstructing gunshot-inflicted composite mandibular defects in males.
5 citations
,
July 1988 in “Facial Plastic Surgery” Tissue expansion is a useful method for reconstructive surgery with good results and room for further enhancement.
1 citations
,
January 2016 in “Elsevier eBooks” This chapter discusses the composition, biocompatibility, and production methods of biomaterials like collagen, chitin, and silk for dermal substitutes, focusing on preclinical and clinical research, but reports no new clinical results.
1 citations
,
November 2002 in “Neurosurgery Clinics of North America” This article reviews the role of androgens in male pattern hair loss and its emotional impact, but reports no new clinical findings.
This study demonstrates that a novel autologous hair follicle-derived epithelial sheet can effectively repigment skin in patients with stable vitiligo, offering a potential new treatment option.
March 2026 in “Frontiers in Cell and Developmental Biology” This meta-analysis found that autologous cell-based therapies, especially stromal vascular fraction, significantly improved atrophic acne scars over control treatments, enhancing both clinical and patient-reported outcomes.
January 2016 in “Springer eBooks” New materials and methods could improve skin healing and reduce scarring.
30 citations
,
December 2017 in “Advanced Healthcare Materials” This study reports that using nanogel and layer-by-layer self-assembly to encapsulate single dermal papilla cells can form cell spheroids that regenerate hair follicles successfully in a hair follicle regeneration model.
3 citations
,
June 2004 in “Alternative and Complementary Therapies” This article reviews the history, biology, genetics, prevention, conventional treatments, and herbal alternatives for hair loss, but reports no new research findings.
July 1998 in “Dermatologic Surgery” Various techniques and tools for hair restoration were presented in 1998, including a mathematical model for donor area, use of lasers in surgery, methods for controlling grafted hair direction, and ways to increase graft yield. Satisfaction rates were around 39%, and studies showed trauma and dehydration can damage hair follicles.
75 citations
,
January 2011 in “Plastic and Reconstructive Surgery” This review discusses the use of dermal regeneration templates for treating burn injuries and other wounds, highlighting their effectiveness in reducing scars and aiding in regenerative processes, but reports no new clinical results.
70 citations
,
February 2021 in “International Journal of Molecular Sciences” This review provides an overview of current research on AD-MSCs, PRP, and biomaterials, highlighting their safety and efficacy in treating soft tissue defects and chronic wounds without major side effects.
1 citations
,
June 2024 in “International Journal of Clinical & Experimental Dermatology” This source outlines various surgical techniques as a potential treatment option for vitiligo, highlighting their usefulness when lesions are resistant to traditional therapies such as topical steroids, calcineurine inhibitors, and biological treatments.
1 citations
,
January 2019 in “Elsevier eBooks” This review discusses scaffold materials and properties used in epidermal tissue engineering to promote skin regeneration and reports no new research findings.
1 citations
,
November 2014 in “Elsevier eBooks” This chapter reviews traditional and tissue-engineered treatments for skin defects and discusses advances in bioengineered skin constructs, but it presents no new experimental results.
March 2026 in “Panacea Journal of Medical Sciences” This study evaluated 23 cases of MRKH syndrome undergoing neo-vaginal reconstruction using islanded pudendal thigh flaps, finding a 100% flap survival and patency rate, along with satisfactory functional and aesthetic outcomes despite minor issues like hair growth in some patients.
June 2024 in “Archives of Plastic Surgery” In this case report, a 44-year-old woman underwent a successful hair transplantation using follicular unit extraction on a myocutaneous free flap, resulting in an 80 to 85% hair survival rate after 12 months and significant improvement in external alopecia aesthetics.