July 2023 in “World Journal of Biology Pharmacy and Health Sciences” This research suggests that the drugs trazodone and chlorpromazine, which have effects on specific receptors, may help restore libido synaptic circuits and potentially treat sexual dysfunction associated with post-SSRI and post-finasteride syndromes.
This study identified pectin in early immature durian fruits and found that pectin-oligosaccharides derived from them show stronger antioxidant and antiglycation activities, with potential applications in cosmetic products.
16 citations
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March 2020 in “Animal Biotechnology” This research explored methods to obtain transgenic sheep embryos expressing synthetic spider silk genes in hair follicles using somatic cell nuclear transfer, with successful in-vitro development observed.
2 citations
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March 2016 in “The Journal of Urology” This study found that the 1 mg dose of finasteride was associated with a wide range of adverse effects, including sexual, psychological, and metabolic symptoms, in the FAERS data.
5 citations
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January 2018 in “Research Journal of Pharmacy and Technology” In this rat study, finasteride treatment significantly reduced body, testis, epididymis, and prostate weights and affected testicular histology, indicating potential negative impacts on testicular function.
October 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that a mild intramuscular dose of BOTOX increased spermatogenesis and improved sperm quality in ageing mice, suggesting potential benefits for managing male infertility.
March 2023 in “The Journal of Urology” This study found that higher baseline expression of SRD5A2 in prostate tissue was associated with a better response to finasteride in men with benign prostatic hyperplasia.
May 2022 in “Reactions Weekly”
1 citations
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September 2013 in “Fertility and Sterility” Finasteride discontinuation increases sperm count in men.
January 2023 in “Bioorganičeskaâ himiâ” This study found that a new deoxycholic acid derivative may offer a similar prostatoprotective effect to finasteride with lower toxicity in rat models.
39 citations
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November 2015 in “Nanomedicine” This study found that the developed Finasteride-loaded SMEDDS improved the relative bioavailability of the drug compared to a commercial tablet, offering a promising oral delivery system for glucosteroid analogs.
2 citations
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January 2019 in “Recent Advances in Biology and Medicine” This study found that a combination of 5% DMSO and BSA minimizes toxic effects on the cytogenetic stability of dermal papilla cells during cryopreservation.
14 citations
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June 1995 in “The Journal of Clinical Endocrinology and Metabolism” 2 citations
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December 2021 in “Pharmaceutics” This study demonstrated that a finasteride-loaded proniosome significantly enhanced transfollicular delivery and hair growth in mice without causing skin irritation, with effects comparable to a 2% minoxidil solution.
3 citations
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October 2015 in “Human Psychopharmacology-clinical and Experimental” In this study, finasteride was found not to be associated with changes in sleep spindle activity or morphology in men undergoing sleep studies.
May 2026 in “Reactions Weekly”
5 citations
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September 2024 in “Stem Cell Research & Therapy” This study found that stem cell transplantation effectively reduced acute inflammation-induced testicular damage, suggesting potential for cell-based therapies in addressing male infertility.
9 citations
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August 2005 in “Experimental Dermatology” In this study, the researchers report that a modified epimorphin-derived peptide shows potential for hair follicle regeneration, especially when used with 1% minoxidil in mice.
This study found that chronic administration of dutasteride in rats did not affect spermatogenesis or oxidative stress in the testes, although it altered hormone levels.
May 2023 in “Journal of pharmacognosy and phytochemistry” This study conducted a comprehensive pharmacognostic and phytochemical analysis of Sphagneticola calendulacea stem, identifying tannin-filled cells, various secondary metabolites, and significant physicochemical characteristics, which could aid in authenticating the plant for therapeutic use.
April 2014 in “The FASEB Journal” This study found that Geranium Sibiricum L extract may promote hair growth by increasing cell proliferation and migration while modulating cytokine expression in human dermal papilla cells under stress conditions.
This study found that a complex extract of Polygonatum sibiricum and Nelumbinis semen improved menopause symptoms in an ovariectomized rat model by enhancing blood lipid metabolism and reducing osteoporosis, without increasing risks of side effects like endometriosis, unlike conventional hormone-replacement therapy.
January 2015 in “INDONESIAN JOURNAL OF PHARMACY” This study developed a simple HPLC method for accurately estimating tamsulosin and finasteride in pharmaceutical forms, demonstrating good precision and potential application in combined dosage analysis.
1 citations
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December 2012 in “I P Pavlov Russian Medical Biological Herald” In this study, finasteride was found to induce tissue-specific P-glycoprotein activity in the liver and kidney of rabbits after a 14-day treatment period.
18 citations
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June 2009 in “Journal of Molecular Endocrinology” This study found that exposure to finasteride impaired spermatogenesis in male Xenopus laevis by affecting sex-specific feedback mechanisms in the hypothalamus–pituitary–gonad axis.
10 citations
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December 2018 in “Medical Science Monitor” This study suggests that the MAPK/ERK signaling pathway plays a role in the regulation of cell proliferation, apoptosis, and cycling in rat urethral plate fibroblasts affected by finasteride-induced hypospadias.
8 citations
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February 2014 in “General and Comparative Endocrinology” In this study, exposure to the drug finasteride in Silurana tropicalis significantly increased testosterone levels in liver and testis tissues and altered gene expression related to male reproduction and oxidative stress.
In this study, finasteride reduced the severity of dopaminergic behavior manifestations in rats without causing extrapyramidal side effects, unlike other antidopaminergic agents.
36 citations
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February 2017 in “BMC Complementary and Alternative Medicine” In this study, Geranium sibiricum L. extract promoted hair growth in vitro with human dermal papilla cells and in vivo in mice, outperforming minoxidil by proliferating cells and stimulating growth factor expression, suggesting its potential as a hair growth treatment.
December 2015 in “Focus on catalysts” This study found that Pomiferin demonstrated potent stimulation of extracellular matrix proteins in human dermal fibroblasts and hair follicles, suggesting its potential as an ingredient in skin and scalp treatments.