Single Injection of Very Mild Dose Botox in the Vastus Lateralis Improves Testicular Spermatogenesis and Sperm Motility in Aging Experimental Mice

October 2021 in “ bioRxiv (Cold Spring Harbor Laboratory) ”

Risna Kanjirassery Radhakrishnan, Sowbarnika Ravichandran, Aishwarya Sukesh, Balamuthu Kadalmani, Mahesh Kandasamy

botulinum toxin type A spermatogenesis sperm motility antioxidants testicular function Botox

TLDR A small BOTOX dose improved sperm production and movement in older mice.

The study investigated the effects of a single, mild dose of BOTOX injected into the vastus lateralis muscle on testicular function in ageing mice. Researchers found that administering 1 U/kg bodyweight of BOTOX improved spermatogenesis and increased sperm count and motility. This was associated with enhanced activity of key antioxidants in the testis. The findings suggested that a minimal intramuscular dose of BOTOX could be a potential treatment strategy for managing and preventing male infertility.

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Single Injection of Very Mild Dose Botox in the Vastus Lateralis Improves Testicular Spermatogenesis and Sperm Motility in Aging Experimental Mice

Research cited in this study

research Effectiveness and Safety of Botulinum Toxin Type A in the Treatment of Androgenetic Alopecia

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