research Influence of 5-Alpha-Reductase Inhibitor Usage on the Reproductive Function of Married Men
Finasteride does not negatively affect male reproductive function.
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510-540 / 879 results research Disorders in Male Sexual Differentiation Due to 5α-Reductase-2 Deficiency
5α-reductase-2 deficiency causes ambiguous genitalia at birth and affects male sexual development, but individuals often develop male characteristics at puberty.
research Finasteride
A man's fertility improved after he stopped taking finasteride but worsened again when he restarted the medication.
research Study the Physiological Effects of Finasteride (Prostacare) on Some Reproductive Parameters in Male Rats (Rattus Rattus)
Finasteride reduces fertility in male rats.
research One of These Things Is Not Like the Others: The Idea of Precedence in Health Technology Assessment and Coverage Decisions
The conclusion is that formalizing how past decisions influence current health technology assessments could improve the credibility and defense of coverage decisions.
research Beliefs and Counseling Practices Among Dermatologists Regarding Sexual and Other Adverse Effects of Finasteride
Many dermatologists believe finasteride can cause sexual side effects and counsel patients about them.
research Pharmacological Activity and Clinical Use of Polydeoxyribonucleotide
PDRN helps repair tissue and improve wound healing with a high safety profile.
research Consequences of Anabolic-Androgenic Steroid Abuse in Males: Sexual and Reproductive Perspective
Using anabolic-androgenic steroids can harm men's reproductive health and increase the risk of heart problems and death.
research Decreased Fertility in Male Rats Administered the 5α-Reductase Inhibitor, Finasteride, Due to Deficits in Copulatory Plug Formation
Finasteride reduces male rat fertility by causing issues with copulatory plug formation.
research Association Between Testicular Microlithiasis and Primary Malignancy of the Testis: Our Experience and Review of the Literature
Testicular microlithiasis may increase the risk of testicular cancer and patients with it should be closely monitored.
research Beneficial Effect of Spironolactone on Androgenic Alopecia
Spironolactone may help reduce hair loss in androgenic alopecia.
research Antiandrogens and the Skin
Antiandrogens can treat acne, hirsutism, and seborrhea by reducing sebum production and androgen action.
research Effects of 2-Ethylhexanoic Acid on Reproduction and Postnatal Development in Wistar Rats
The study investigated the reproductive toxicity of 2-ethylhexanoic acid (2-EHA) in Wistar rats, with 24 animals per sex per group receiving doses of 100, 300, or 600 mg/kg. Results showed a dose-dependent decrease in fertility, with increased time to mating and total infertility at higher doses. Male rats exhibited decreased sperm quality, with reduced motility and increased abnormal sperm at higher doses. The average litter size decreased by 16% at 600 mg/kg, and while birth weights were unaffected, body weight gain during lactation was slower. Pups showed delayed physical development and abnormal features at higher doses. A single 600 mg/kg dose given to pregnant females reduced implantations and caused resorptions. The study concluded that 2-EHA impaired fertility and delayed postnatal development, likely due to disturbed implantation and teratogenic effects.
research Pregnancy Outcomes with Paternal Exposure to Finasteride, a Synthetic 5-Alpha-Reductase Inhibitor: A Case Series
Babies were mostly born healthy from fathers who took finasteride, but some pregnancies ended early; more research is needed.
research The Effect of 5-Alpha Reductase Inhibitor on Male Reproductive Function
5-α reductase inhibitors do not significantly affect male reproductive function but may reduce semen volume.
research Development of New Treatment Modality for Male Infertility Using Phytopharmaceuticals
MOTILIPERM may help treat male infertility by reducing stress in cells.
research Does Imipramine and Pseudoephedrine Medical Treatment Have Clinical Implications in the Treatment of Retrograde Ejaculation Caused by Diabetes Mellitus?
Imipramine and pseudoephedrine treatment can effectively restore normal ejaculation in patients with diabetes, increasing their chances for pregnancy.
research Total Prostate Volume as Risk Factor for Semen Pathologies in Aging Male
Larger prostate size in older men may be linked to poorer semen quality and fertility issues.
research This Month in Clinical Urology
New treatments and diagnostic methods for urological conditions show promise, but some lack sufficient accuracy for clinical use.
research Let Astaxanthin Be Thy Medicine
Astaxanthin is a safe antioxidant that may improve heart, skin, eye health, and physical performance, and help manage chronic diseases.
research Art’s Work in the Age of Biotechnology: Shaping Our Genetic Futures
The exhibition made people think about ethics and society in relation to biotech advances.
research Protective Effect of DA-9401 in Finasteride-Induced Apoptosis in Rat Testis: Inositol Requiring Kinase 1 and c-Jun N-Terminal Kinase Pathway
Finasteride helps female-pattern hair loss.
research Androgenetic Alopecia: Effects of Oral Finasteride on Hormone Profile, Reproduction, and Sexual Function
Finasteride safely treats hair loss without harming hormones or reproduction, but may slightly reduce sexual function.
research 5α-Reductase Inhibitor Therapy: Should Physicians Be Concerned With Persistent Diminished Libido, Erectile Dysfunction, and Depression in a Subset of Patients?
Some patients may experience lasting sexual dysfunction, depression, and other side effects from 5α-reductase inhibitor therapy.
research Study of SARS-CoV-2 in Semen and Urine Samples of a Volunteer with Positive Nasopharyngeal Swab
The virus was not found in the semen and urine of a man who tested positive for COVID-19.
research Action of Isotretinoin in Acne Rosacea and Gram-Negative Folliculitis
Isotretinoin is highly effective in treating severe acne, rosacea, and gram-negative folliculitis.
research The Transcriptional Repressor CDP (Cutl1) Is Essential for Epithelial Cell Differentiation of the Lung and the Hair Follicle
CDP is crucial for lung and hair follicle cell development.
research Effects of Dermatological Medications on Male Fertility
Some dermatological medications can impair male fertility, so consult a doctor before trying to conceive.
research Graded Levels of Pyridoxine in the Rat Diet During Gestation and the Physical and Neuromotor Development of Offspring
Not enough vitamin B6 in pregnant rats' diets caused poor development and health in their babies.
research Investigation of the Plausibility of 5-Alpha-Reductase Inhibitor Syndrome
The document concludes that sexual and psychiatric side effects from 5-alpha-reductase inhibitors are reported, but more high-quality research is needed to understand how often they occur.