A Mutation of the Androgen Receptor Associated with Partial Androgen Resistance, Familial Gynecomastia, and Fertility
April 1988
in “
The Journal of Clinical Endocrinology & Metabolism
”
androgen receptor partial androgen resistance gynecomastia undervirilization X-linked inheritance supranormal serum testosterone LH FSH oligospermia sperm motility androgen binding thermolabile receptor up-regulation dissociation rates androgen receptor protein cytosol preparations testosterone luteinizing hormone follicle-stimulating hormone sperm count sperm movement
Studysummary This study describes a family with X-linked gynecomastia and undervirilization in men, finding a subtle androgen receptor abnormality that may not always lead to infertility despite androgen resistance.
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