1 citations
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November 2023 in “Biomaterials advances” This study found that combining mesenchymal stromal cells from adipose tissue and hair follicles with soy protein and β-chitin scaffolds significantly reduced wound healing time and improved skin regeneration in vivo.
12 citations
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November 2024 in “Plants” This study found that the phytosterols β-sitosterol, stigmasterol, and campesterol have low-to-negligible inhibitory activity against steroidal 5α-reductase type 2 compared to the synthetic inhibitor dutasteride, with β-sitosterol showing the highest activity among the tested phytosterols.
2 citations
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November 1955 in “Archives of dermatology” In this report of a pediatric alopecia case, cortisone and ACTH gel treatments did not result in significant nail improvement, but there was considerable scalp hair regrowth.
December 2019 in “Thèses en ligne de l'Université Toulouse III (Université Toulouse III)” This study found that the expression of the protein SOX2 is associated with the potential for beige adipocyte formation and adipocyte plasticity in both human and mouse models.
December 2025 in “Advanced Healthcare Materials” This study introduces a spherical skin model that effectively mimics key features of human skin, offering a scalable and rapid alternative for non-animal dermatological and cosmetic testing.
This trial explores whether spironolactone is more effective than cyclines for treating moderate acne in adult women, providing a potential alternative amidst concerns over antibiotic resistance.
22 citations
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May 2011 in “European Journal of Cancer” This phase I study determined that a combination of oral SU-014813 and docetaxel is a feasible treatment with a manageable safety profile and potential anti-tumor activity, particularly noted in melanoma and GIST patients.
52 citations
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May 2011 in “Journal of Neuroendocrinology” This study found that palmitoylethanolamide may stimulate allopregnanolone synthesis and reduce oxidative stress in astrocytes through PPAR-α activation, suggesting a neuroprotective role.
May 2021 in “Journal of the Endocrine Society” This case study reports a patient with ACTH-driven cortisol secretion 14 years after adrenalectomy, suggesting possible residual adrenal tissue or extra-adrenal steroid synthesis, challenging the need for lifelong steroid replacement.
29 citations
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January 2020 in “BioMed Research International” This study found that sinapic acid promotes the browning of 3T3-L1 adipocytes and may offer therapeutic potential for obesity by influencing mitochondrial biogenesis through the p38 MAPK/CREB signaling pathway.
22 citations
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November 2017 in “Scientific Reports” This study found that, despite a major depletion of SOX2-expressing stem cells in the pituitary, there was no effect on endocrine cell homeostasis or response to certain stressors in adult mice.
22 citations
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December 2020 in “mSphere” This study identified a fungal sulfotransferase enzyme, FgSULT1, from *Fusarium graminearum*, expanding the sulfotransferase superfamily and offering new biocatalytic methods for producing bioactive sulfates.
1 citations
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August 2023 in “Austin Chemical Engineering” In this study, researchers developed hair and foot care products using tofu whey instead of water, highlighting its potential to conserve water and utilize protein-rich waste, though specific efficacy results are not reported.
July 2022 in “Asian Journal of Biochemistry, Genetics and Molecular Biology” This study found that Ageratum conyzoides showed antihyperglycemic and antilipidemic effects in diabetic rats, with significant changes in hematological and serum electrolyte parameters at 2000mg/kg.
1 citations
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February 2023 in “Animals” In this study, the inclusion of a feedstuff high in energy along with soybean meal enhanced body condition, body mass index, and reproductive performance in sheep fed low-protein forage.
3 citations
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April 2016 in “Research and reports in urology” In a cell-free test setting, this study found that a novel saw palmetto extract effectively inhibited the 5α-reductase type II enzyme, showing promising bioactivity comparable to finasteride for promoting prostate health.
May 2026 in “SKIN The Journal of Cutaneous Medicine” This study found that the nutraceutical gummy Xtressé™ may promote hair density and follicular growth in women with perceived hair thinning, offering a user-friendly alternative to traditional supplements.
2 citations
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May 2020 in “Molecules” This paper describes the synthesis of (16S,20S)-3β-hydroxy-5α-pregnane-20,16-carbolactam from tigogenin without presenting new experimental results.
March 2022 in “VNU Journal of Science Medical and Pharmaceutical Sciences” This study developed a sensitive method using LC-ESI-MS/MS for accurate and reliable measurement of nine steroid hormones in children's serum.
April 2026 in “International Journal of Drug Delivery Technology” This study found that Lactobacillus acidophilus cell-free supernatant caused significant cytotoxicity, reduced migratory ability, and induced apoptosis in cervical cancer cell lines, suggesting its potential as a non-toxic adjunct therapy for cervical cancer.
January 2017 in “Nutrafoods - International Journal on Nutraceuticals, Functional Foods and Novel Foods” This study found that a dietary supplement containing fermented soy, ornithine, arginine, and Tricovel® Tricoage45+ significantly reduced hair loss and promoted hair growth in menopausal women after 8 to 12 weeks.
1 citations
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January 2010 in “Journal of Oriental Medicine” Black bean, wheat, and rice bran extracts can boost hair growth and improve hair quality.
8 citations
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April 2022 in “Nutrients” In this study, Ishige sinicola extract was observed to improve bone density and structure in an animal model of estrogen deficiency-induced osteoporosis, suggesting its potential as a therapeutic option for postmenopausal osteoporosis by inhibiting osteoclast formation without cytotoxic effects.
9 citations
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June 2020 in “Trials” This study aims to conduct the first double-blind randomized trial comparing spironolactone and doxycycline for female acne treatment, with the goal of establishing spironolactone as a potentially superior alternative, especially given concerns about antibiotic resistance.
This study suggests that shiitake mushroom, buckwheat, soybean, cypress, and seaweed fulvescens may be potential candidates for use in scalp care cosmetics due to their antioxidative and antimicrobial properties, safety, and favorable user feedback.
September 2023 in “Journal of the American Academy of Dermatology” In this study, a cleanser gel with salicylic acid, vitamin C, and Lens esculenta seed extract reduced facial oiliness by 44.9% after 2 hours and by 19.1% after 4 hours in subjects with oily skin, using a novel facial oiliness mapping method.
April 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” This study identified intramembrane proteolysis as a key feature of Astrotactin2 maturation, providing insights into its role in planar cell polarity hair patterning.
June 2023 in “Trichology and cosmetology:” This study found that 12-week oral supplementation of Ageratum conyzoides extract significantly reduced hairline recession and affected prostaglandin levels in adults with hair loss, though hair density increases were not statistically significant, and no improvements were found in other hair loss measures compared to placebo.
1 citations
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September 2023 in “Molecules (Basel. Online)” This source highlights that while plant sterols show potential benefits and applications in various industries, significant research gaps, including their complex structures and mechanisms, hinder their broader use, emphasizing the need for innovative sources and sustainable methods for their study.
4 citations
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January 1989 in “Journal of Steroid Biochemistry” This study suggests that 5-ADIOL-S may contribute to the synthesis of potent androgens in peripheral tissues, and 3 alpha-DIOL-S could be a marker of androgen metabolism in various female patient groups.