The Brown Algae Ishige Sinicola Extract Ameliorates Ovariectomy-Induced Bone Loss in Rats and Suppresses Osteoclastogenesis Through Downregulation of NFATc1/c-Fos

    April 2022 in “ Nutrients ”
    Mihyang Kim, Mihwa Park
    Studysummary In this study, Ishige sinicola extract was observed to improve bone density and structure in an animal model of estrogen deficiency-induced osteoporosis, suggesting its potential as a therapeutic option for postmenopausal osteoporosis by inhibiting osteoclast formation without cytotoxic effects.
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    Research cited in this study 2

    1. Ishige Sinicola Extract Stimulates Osteoblast Proliferation and Differentiation via the Bone Morphogenetic Protein 2/Runt-Related Gene 2 Signaling Pathway Zeitschrift für Naturforschung C · 2019
    2. The Promoting Effect of Ishige Sinicola on Hair Growth Marine Drugs · 2013