FASCE: The Benefit of Spironolactone for Treating Acne in Women - Study Protocol for a Randomized Double-Blind Trial

    June 2020 in “ Trials ”
    Alexandra Poinas, M Lemoigne, S. Le Naour … Brigitte Dréno
    Studysummary This study aims to conduct the first double-blind randomized trial comparing spironolactone and doxycycline for female acne treatment, with the goal of establishing spironolactone as a potentially superior alternative, especially given concerns about antibiotic resistance.
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    Research cited in this study 5

    1. Oral Spironolactone for Acne Vulgaris in Adult Females: A Hybrid Systematic Review American Journal of Clinical Dermatology · 2017
    2. Hormonal Therapy for Acne Seminars in Cutaneous Medicine and Surgery · 2008
    3. Acne The New England Journal of Medicine · 2005
    4. Update and Future of Hormonal Therapy in Acne Dermatology · 2003
    5. Oral Spironolactone Therapy for Female Patients with Acne, Hirsutism, or Androgenic Alopecia British Journal of Dermatology · 1985