Sinapic Acid Promotes Browning of 3T3-L1 Adipocytes via p38 MAPK/CREB Pathway

    January 2020 in “ BioMed Research International ”
    In-Seon Bae, Sang Hoon Kim
    TLDR Sinapic acid may help fight obesity and promote hair growth.
    The study found that sinapic acid promoted the browning of 3T3-L1 adipocytes by activating the AMPK, p38 MAPK, and CREB pathways, leading to increased expression of thermogenic and beige-specific genes. This process enhanced mitochondrial biogenesis and function, suggesting sinapic acid as a potential anti-obesity agent. It was effective at lower concentrations than other similar compounds, potentially reducing side effects. Additionally, sinapic acid showed promise in promoting hair growth in human hair follicle dermal papilla cells, indicating its varied mechanism of action across different cell types.
    Discuss this study in the Community →

    Research cited in this study

    1 / 1 results

    Related Community Posts Join

    1 / 1 results

      community Natural Remedies: Polyphenols and Hair Loss

       20 upvotes 6 years ago
      Natural remedies to treat hair loss, such as polyphenols, apple peel extract, grape seed extract, green tea extract, peppermint oil, pumpkin seed oil, apigenin, Ginkgo biloba, red clover extract, olive leaf extract, Ecklonia Cava and Grateloupia elliptica. In addition, terpenes, carotenoids, and tocopherols were discussed as potential treatments.

    Similar Research

    5 / 59 results